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| On May 6, 2013, the ] approved the first two commercial pesticide products that contain sulfoxaflor, marketed under the brand names "Transform" and "Closer", to the Dow Chemical Corporation. This pesticide has been registered to South Korea, Panama, Vietnam, Indonesia, and Guatemala and additional global registrations are expected in the near future. | On May 6, 2013, the ] approved the first two commercial pesticide products that contain sulfoxaflor, marketed under the brand names "Transform" and "Closer", to the Dow Chemical Corporation. This pesticide has been registered to South Korea, Panama, Vietnam, Indonesia, and Guatemala and additional global registrations are expected in the near future. | ||
| However, on 10 September 2015 the ] issued a ruling overturning the EPA's approval of sulfoxaflor.<ref>{{http://www.latimes.com/local/lanow/la-me-ln-bees-insecticide-20150910-story.html}}</ref> | However, on 10 September 2015 the ] issued a ruling overturning the EPA's approval of sulfoxaflor.<ref>{{cite web|url=http://www.latimes.com/local/lanow/la-me-ln-bees-insecticide-20150910-story.html}}</ref> | ||
| ==See also== | ==See also== | ||
| *] | *] | ||
Revision as of 21:42, 10 September 2015
 | |
| Names | |
|---|---|
| IUPAC name ethyl}-λ-sulfanylidene]cyanamide | |
| Identifiers | |
| CAS Number | |
| ECHA InfoCard | 100.234.961 
|
| CompTox Dashboard (EPA) | |
InChI
| |
| Properties | |
| Chemical formula | C10H10F3N3OS |
| Molar mass | 277.27 g·mol |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references | |
Sulfoxaflor is a systemic insecticide which acts as an insect neurotoxin and is the first member a class of chemicals called the sulfoximines which act on the central nervous system of insects with much lower toxicity to mammals. The chemical works by interfering with the transmission of stimuli in the insect nervous system. Specifically, it causes a blockage in the nicotinergic neuronal pathway. This blockage leads to the accumulation of acetylcholine, an important neurotransmitter, resulting in the insect's paralysis, and eventually death. It is effective on contact and via stomach action. Because sulfoxaflor binds much more strongly to insect neuron receptors than to mammal neuron receptors, this insecticide is selectively more toxic to insects than mammals.
On May 6, 2013, the United States Environmental Protection Agency approved the first two commercial pesticide products that contain sulfoxaflor, marketed under the brand names "Transform" and "Closer", to the Dow Chemical Corporation. This pesticide has been registered to South Korea, Panama, Vietnam, Indonesia, and Guatemala and additional global registrations are expected in the near future.
However, on 10 September 2015 the U.S. 9th Circuit Court of Appeals issued a ruling overturning the EPA's approval of sulfoxaflor.
See also
References
- Sparks, Thomas C. (2013). "Sulfoxaflor and the sulfoximine insecticides: Chemistry, mode of action and basis for efficacy on resistant insects". Pesticide Biochemistry and Physiology. 107 (1): 1–7. doi:10.1016/j.pestbp.2013.05.014.
- Cutler, P.; Slater, R.; Edmunds, A. J.; Maienfisch, P.; Hall, R. G.; Earley, F. G.; Pitterna, T.; Pal, S.; Paul, V. L.; Goodchild, J.; Blacker, M.; Hagmann, L.; Crossthwaite, A. J. (2013). "Investigating the mode of action of sulfoxaflor: A fourth-generation neonicotinoid". Pest Management Science. 69 (5): 607–619. doi:10.1002/ps.3413. PMID 23112103.
- "sulfoxaflor". ChemSpider. Royal Society of Chemistry. Retrieved 19 August 2013.
- http://www.latimes.com/local/lanow/la-me-ln-bees-insecticide-20150910-story.html.
{{cite web}}: Missing or empty|title=(help)
External links
- The EPA’s Final Decision on the New Active Ingredient Sulfoxaflor
- Dow AgroSciences Receives U.S. EPA Registration for Sulfoxaflor Dow AgroSciences Receives U.S. EPA Registration for Sulfoxaflor (Press release)