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Xanthosine triphosphate: Difference between revisions

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Revision as of 16:52, 17 December 2010 editCheMoBot (talk | contribs)Bots141,565 edits Updating {{chembox}} (no changed fields - added verified revid - updated 'UNII_Ref', 'ChemSpiderID_Ref', 'StdInChI_Ref', 'StdInChIKey_Ref') per Chem/Drugbox validation (report [[Wikipedia_talk:Wi← Previous edit Latest revision as of 21:11, 17 November 2020 edit undoWaacstats (talk | contribs)Autopatrolled, Extended confirmed users, Pending changes reviewers1,348,587 editsm –{{Organic-compound-stub}} using StubSorter 
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{{Orphan|date=February 2009}}
{{chembox {{chembox
| Verifiedfields = changed
| verifiedrevid = 402880365 | verifiedrevid = 470633067
|ImageFile=xanthosine triphosphate.png | ImageFile=xanthosine triphosphate.png
|ImageSize=200px | ImageSize=200px
|IUPACName=methyl (hydroxy-phosphonooxyphosphoryl) hydrogen phosphate | IUPACName=methyl (hydroxy-phosphonooxyphosphoryl) hydrogen phosphate
|OtherNames= | OtherNames=
|Section1= {{Chembox Identifiers |Section1={{Chembox Identifiers
| InChI = 1/C10H12N4O6.3H3O4P/c15-1-3-5(16)6(17)9(20-3)14-2-11-4-7(14)12-10(19)13-8(4)18;3*1-5(2,3)4/h2-3,5-6,9,15-17H,1H2,(H2,12,13,18,19);3*(H3,1,2,3,4)/t3-,5-,6-,9-;;;/m1.../s1 | InChI = 1/C10H12N4O6.3H3O4P/c15-1-3-5(16)6(17)9(20-3)14-2-11-4-7(14)12-10(19)13-8(4)18;3*1-5(2,3)4/h2-3,5-6,9,15-17H,1H2,(H2,12,13,18,19);3*(H3,1,2,3,4)/t3-,5-,6-,9-;;;/m1.../s1
| InChIKey = BKBQKVXTMZOVRH-CYCLDIHTBT | InChIKey = BKBQKVXTMZOVRH-CYCLDIHTBT
| StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI_Ref = {{stdinchicite|correct|chemspider}}
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = BKBQKVXTMZOVRH-CYCLDIHTSA-N | StdInChIKey = BKBQKVXTMZOVRH-CYCLDIHTSA-N
| CASNo_Ref = {{cascite|changed|??}}
| CASNo=6253-56-1 | CASNo=6253-56-1
| PubChem=121887 | PubChem=121887
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID=19980202 | ChemSpiderID=19980202
| SMILES = OP(O)(=O)O.OP(O)(=O)O.OP(O)(=O)O.O=C3Nc2c(ncn21O(CO)(O)1O)C(=O)N3 | SMILES = OP(O)(=O)O.OP(O)(=O)O.OP(O)(=O)O.O=C3Nc2c(ncn21O(CO)(O)1O)C(=O)N3
}} }}
|Section2= {{Chembox Properties |Section2={{Chembox Properties
| Formula=C<sub>10</sub>H<sub>15</sub>N<sub>4</sub>O<sub>15</sub>P<sub>3</sub> | Formula=C<sub>10</sub>H<sub>15</sub>N<sub>4</sub>O<sub>15</sub>P<sub>3</sub>
| MolarMass=524.17 g/mol | MolarMass=524.17 g/mol
| Appearance= | Appearance=
| Density= | Density=
| MeltingPt= | MeltingPt=
| BoilingPt= | BoilingPt=
| Solubility= | Solubility=
}} }}
|Section3= {{Chembox Hazards |Section3={{Chembox Hazards
| MainHazards= | MainHazards=
| FlashPt= | FlashPt=
| AutoignitionPt =
| Autoignition=
}} }}
}} }}


'''Xanthosine 5'-triphosphate''' ('''XTP''') is a ] that is not produced by - and has no known function in - living cells. Uses of XTP are, in general, limited to experimental procedures on enzymes that bind other nucleotides. '''Xanthosine 5'-triphosphate''' ('''XTP''') is a ] that is not produced by - and has no known function in - living cells. Uses of XTP are, in general, limited to experimental procedures on enzymes that bind other nucleotides. Deamination of purine bases can result in accumulation of such nucleotides as ], ], XTP, and ].<ref name="pmid 22531138">{{cite journal | vauthors = Davies O, Mendes P, Smallbone K, Malys N | title = Characterisation of multiple substrate-specific (d)ITP/(d)XTPase and modelling of deaminated purine nucleotide metabolism | journal = BMB Reports | volume = 45 | issue = 4 | pages = 259–64 | year = 2012 | pmid = 22531138| doi = 10.5483/BMBRep.2012.45.4.259 | doi-access = free }}</ref>

==References==
{{reflist}}


==See also== ==See also==
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{{organic-compound-stub}} {{Alkaloid-stub}}
{{biochemistry-stub}}

Latest revision as of 21:11, 17 November 2020

Xanthosine triphosphate
Names
IUPAC name methyl (hydroxy-phosphonooxyphosphoryl) hydrogen phosphate
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
PubChem CID
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C10H12N4O6.3H3O4P/c15-1-3-5(16)6(17)9(20-3)14-2-11-4-7(14)12-10(19)13-8(4)18;3*1-5(2,3)4/h2-3,5-6,9,15-17H,1H2,(H2,12,13,18,19);3*(H3,1,2,3,4)/t3-,5-,6-,9-;;;/m1.../s1Key: BKBQKVXTMZOVRH-CYCLDIHTSA-N
  • InChI=1/C10H12N4O6.3H3O4P/c15-1-3-5(16)6(17)9(20-3)14-2-11-4-7(14)12-10(19)13-8(4)18;3*1-5(2,3)4/h2-3,5-6,9,15-17H,1H2,(H2,12,13,18,19);3*(H3,1,2,3,4)/t3-,5-,6-,9-;;;/m1.../s1Key: BKBQKVXTMZOVRH-CYCLDIHTBT
SMILES
  • OP(O)(=O)O.OP(O)(=O)O.OP(O)(=O)O.O=C3Nc2c(ncn21O(CO)(O)1O)C(=O)N3
Properties
Chemical formula C10H15N4O15P3
Molar mass 524.17 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). ☒verify (what is  ?) Infobox references
Chemical compound

Xanthosine 5'-triphosphate (XTP) is a nucleotide that is not produced by - and has no known function in - living cells. Uses of XTP are, in general, limited to experimental procedures on enzymes that bind other nucleotides. Deamination of purine bases can result in accumulation of such nucleotides as ITP, dITP, XTP, and dXTP.

References

  1. Davies O, Mendes P, Smallbone K, Malys N (2012). "Characterisation of multiple substrate-specific (d)ITP/(d)XTPase and modelling of deaminated purine nucleotide metabolism". BMB Reports. 45 (4): 259–64. doi:10.5483/BMBRep.2012.45.4.259. PMID 22531138.

See also

Nucleic acid constituents
Nucleobase
Nucleoside
Ribonucleoside
Deoxyribonucleoside
Nucleotide
(Nucleoside monophosphate)
Ribonucleotide
Deoxyribonucleotide
Cyclic nucleotide
Nucleoside diphosphate
Nucleoside triphosphate


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