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TAN-1057 C: Difference between revisions

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{{Chembox {{Chembox
| Verifiedfields = changed
| verifiedrevid = 401615853 | verifiedrevid = 470482224
| Name=TAN-1057 C <small>(top)</small> and TAN-1057 D <small>(bottom)</small>
| Name={{nowrap|TAN-1057 C}} and {{nowrap|TAN-1057 D}}
| ImageFile1 = TAN-1057C.png | ImageFile1 = TAN-1057C.png
| ImageSize1 = 200px | ImageSize1 =
| ImageAlt1 = TAN-1057 C
| ImageCaption1 = TAN-1057 C
| ImageFile2 = TAN-1057D.png | ImageFile2 = TAN-1057D.png
| ImageAlt2 = TAN-1057 D
| ImageSize2 = 200px
| ImageCaption2 = TAN-1057 D
| IUPACName =
| OtherNames = | IUPACName =
| OtherNames =
| Section1 = {{Chembox Identifiers | Section1 = {{Chembox Identifiers
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = PNFFUPQADHHLMN-DTWKUNHWSA-N | StdInChIKey = PNFFUPQADHHLMN-DTWKUNHWSA-N
| CASNo_Ref = {{cascite|changed|??}}
⚫ | CASNo = 128126-46-5
| CASOther = &nbsp;(TAN-1057 C)<br>128126-47-6 (TAN-1057 D) | CASNo = 128126-46-5
| CASNo_Comment = (TAN-1057 C)
| CASNo2_Ref = {{cascite|changed|??}}
⚫ | CASNo2 = 128126-47-6
| CASNo2_Comment = (TAN-1057 D)
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 7TWX2V5P6Q
| PubChem = 9576889 | PubChem = 9576889
| SMILES = O=C1N(C)(C(=O)N(C1)CCC/N=C(\N)N)CNN\C=N\C(=O)N | SMILES = O=C1N(C)(C(=O)N(C1)CCC/N=C(\N)N)CNN\C=N\C(=O)N
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| Section2 = {{Chembox Properties | Section2 = {{Chembox Properties
| C=13| H=25| N=9| O=3 | C=13| H=25| N=9| O=3
| Appearance = | Appearance =
| Density = | Density =
| MeltingPt = | MeltingPt =
| BoilingPt = | BoilingPt =
| Solubility = }} | Solubility = }}
| Section3 = {{Chembox Hazards | Section3 = {{Chembox Hazards
| MainHazards = | MainHazards =
| FlashPt = | FlashPt =
| Autoignition = }} | AutoignitionPt = }}
}} }}


'''TAN-1057 C''' and '''TAN-1057 D''' are organic compounds found in the ''] sp.'' PK-74 bacterium. TAN-1057 C and D are closely related structurally as ]s. Also related are ] and TAN-1057 B, isolated from the same bacteria. The four compounds have been shown to be an effective ]s against ]-resistant strains of '']'' which act through the inhibition of ] biosynthesis.<ref name=Katayama>{{cite journal | author=Katayama, N ''et al.'' | title=TAN-1057 A-D, new antibiotics with potent antibacterial activity against methicillin-resistant Staphylococcus aureus. Taxonomy, fermentation and biological activity | journal=J. Antibiot. | year=1993 | pages=606–613 | volume=46 | issue=4 | pmid=8501003}}</ref> '''TAN-1057 C''' and '''TAN-1057 D''' are organic compounds found in the ''] sp.'' PK-74 bacterium. TAN-1057 C and D are closely related structurally as ]s. Also related are ] and TAN-1057 B, isolated from the same bacteria. The four compounds have been shown to be an effective ]s against ]-resistant strains of '']'' which act through the inhibition of ] biosynthesis.<ref name=Katayama>{{cite journal | author=Katayama, N| title=TAN-1057 A-D, new antibiotics with potent antibacterial activity against methicillin-resistant Staphylococcus aureus. Taxonomy, fermentation and biological activity | journal=J. Antibiot. | year=1993 | pages=606–613 | volume=46 | issue=4 | pmid=8501003 | doi=10.7164/antibiotics.46.606|display-authors=etal| doi-access=free }}</ref>


==References== ==References==
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] ]
] ]
] ]




Latest revision as of 13:55, 9 January 2023

TAN-1057 C and TAN-1057 D
TAN-1057 C
TAN-1057 C
TAN-1057 D
TAN-1057 D
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C13H25N9O3/c1-22-9(6-19-20-7-18-13(16)25)11(24)21-8(5-10(22)23)3-2-4-17-12(14)15/h7-9,19H,2-6H2,1H3,(H,21,24)(H4,14,15,17)(H3,16,18,20,25)/t8-,9+/m0/s1Key: PNFFUPQADHHLMN-DTWKUNHWSA-N
  • InChI=1/C13H25N9O3/c1-22-9(6-19-20-7-18-13(16)25)11(24)21-8(5-10(22)23)3-2-4-17-12(14)15/h7-9,19H,2-6H2,1H3,(H,21,24)(H4,14,15,17)(H3,16,18,20,25)/t8-,9+/m0/s1Key: PNFFUPQADHHLMN-DTWKUNHWBI
SMILES
  • O=C1N(C)(C(=O)N(C1)CCC/N=C(\N)N)CNN\C=N\C(=O)N
Properties
Chemical formula C13H25N9O3
Molar mass 355.403 g·mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). ☒N verify (what is  ?) Infobox references
Chemical compound

TAN-1057 C and TAN-1057 D are organic compounds found in the Flexibacter sp. PK-74 bacterium. TAN-1057 C and D are closely related structurally as diastereomers. Also related are TAN-1057 A and TAN-1057 B, isolated from the same bacteria. The four compounds have been shown to be an effective antibiotics against methicillin-resistant strains of Staphylococcus aureus which act through the inhibition of protein biosynthesis.

References

  1. Katayama, N; et al. (1993). "TAN-1057 A-D, new antibiotics with potent antibacterial activity against methicillin-resistant Staphylococcus aureus. Taxonomy, fermentation and biological activity". J. Antibiot. 46 (4): 606–613. doi:10.7164/antibiotics.46.606. PMID 8501003.


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