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Sevirumab: Difference between revisions

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Revision as of 22:42, 13 November 2011 editCheMoBot (talk | contribs)Bots141,565 edits Updating {{drugbox}} (changes to verified fields - updated 'ChemSpiderID_Ref', 'UNII_Ref', 'ChEMBL_Ref', 'ChEBI_Ref', 'KEGG_Ref', 'StdInChI_Ref', 'StdInChIKey_Ref') per Chem/Drugbox validation (report [[Misplaced Pages talk:WikiProject_...← Previous edit Latest revision as of 20:54, 1 December 2023 edit undoBuidhe (talk | contribs)Autopatrolled, Extended confirmed users, Page movers, File movers, Mass message senders, New page reviewers, Pending changes reviewers, Template editors136,149 editsm Moving from Category:Experimental drugs to Category:Experimental antiviral drugs using Cat-a-lot 
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{{Short description|Monoclonal antibody}}
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<!-- Monoclonal antibody data -->
| verifiedrevid = 447741609

<!--Monoclonal antibody data-->
| type = mab | type = mab
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| source = u | source = u
| target = ] | target = ]
<!-- Clinical data -->

<!--Clinical data-->
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'''Sevirumab''' ('''MSL-109''') is a ] ] for the treatment of infections with ] in patients with ].<ref>{{cite journal|pmid=15498605|year=2004|last1=Borucki|first1=MJ|last2=Spritzler|last3=Asmuth|last4=Gnann|last5=Hirsch|last6=Nokta|last7=Aweeka|last8=Nadler|last9=Sattler|title=A phase II, double-masked, randomized, placebo-controlled evaluation of a human monoclonal anti-Cytomegalovirus antibody (MSL-109) in combination with standard therapy versus standard therapy alone in the treatment of AIDS patients with Cytomegalovirus retinitis|volume=64|issue=2|pages=103–11|doi=10.1016/j.antiviral.2004.06.012|journal=Antiviral research|first2=J|first3=DM|first4=J|first5=MS|first6=M|first7=F|first8=PI|first9=F}}</ref><ref></ref> '''Sevirumab''' ('''MSL-109''') is a ] ] for the treatment of infections with ] in patients with ].<ref>{{cite journal | vauthors = Borucki MJ, Spritzler J, Asmuth DM, Gnann J, Hirsch MS, Nokta M, Aweeka F, Nadler PI, Sattler F, Alston B, Nevin TT, Owens S, Waterman K, Hubbard L, Caliendo A, Pollard RB | display-authors = 6 | title = A phase II, double-masked, randomized, placebo-controlled evaluation of a human monoclonal anti-Cytomegalovirus antibody (MSL-109) in combination with standard therapy versus standard therapy alone in the treatment of AIDS patients with Cytomegalovirus retinitis | journal = Antiviral Research | volume = 64 | issue = 2 | pages = 103–11 | date = November 2004 | pmid = 15498605 | doi = 10.1016/j.antiviral.2004.06.012 }}</ref><ref>{{ClinicalTrialsGov|NCT00000836|A Phase II/III Trial of Human Anti-CMV Monoclonal Antibody MSL 109 (MACRT)}}</ref>


==References== == References ==
{{reflist}} {{reflist}}


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]


{{antiinfective-drug-stub}} {{antiinfective-drug-stub}}
{{monoclonal-antibody-stub}} {{monoclonal-antibody-stub}}

Latest revision as of 20:54, 1 December 2023

Monoclonal antibody Pharmaceutical compound
Sevirumab
Monoclonal antibody
Type?
SourceHuman
TargetCMV
Clinical data
ATC code
  • none
Identifiers
CAS Number
ChemSpider
  • none
UNII
KEGG
ChEMBL
  (verify)

Sevirumab (MSL-109) is a human monoclonal antibody for the treatment of infections with cytomegalovirus in patients with AIDS.

References

  1. Borucki MJ, Spritzler J, Asmuth DM, Gnann J, Hirsch MS, Nokta M, et al. (November 2004). "A phase II, double-masked, randomized, placebo-controlled evaluation of a human monoclonal anti-Cytomegalovirus antibody (MSL-109) in combination with standard therapy versus standard therapy alone in the treatment of AIDS patients with Cytomegalovirus retinitis". Antiviral Research. 64 (2): 103–11. doi:10.1016/j.antiviral.2004.06.012. PMID 15498605.
  2. Clinical trial number NCT00000836 for "A Phase II/III Trial of Human Anti-CMV Monoclonal Antibody MSL 109 (MACRT)" at ClinicalTrials.gov
Monoclonal antibodies for infectious disease and toxins
Fungal
Human
Viral
Human
Chimeric
Humanized
Bacterial
Human
Mouse
Chimeric
Humanized
Toxin
Human
Chimeric
Humanized
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