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Microbiology C‑class Mid‑importance

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Chiron link

• I've pulled the Chiron link (http://chiron.com/041008_testimony.pdf); it appears to be dead and my search for an archived copy (Wayback Machine, etc) didn't turn up anything. If anyone can find a link, we can stick it back in. -- MarcoTolo 21:54, 3 May 2006 (UTC)

  @MarcoTolo: The file is in the Wayback Machine. You just need the first snapshot: https://web.archive.org/web/20050505000037/http://www.chiron.com/041008_testimony.pdf I tracked your comment to your edit: . I've read the document, the article, and the diff, but I do not understand how Chiron may be relevant to the article. The only part mentioning the bacteria in the document is "…that in conducting final internal release procedures for our Fluvirin® influenza virus vaccine, our quality systems identified a small number of lots that did not meet product sterility specifications. This related to contamination with Serratia marcescens." This somewhat supports the statement in the article that "The first indications of problems with the influenza vaccine produced by Chiron Corporation in 2004 involved S. marcescens contamination." But I do not see any benefit to the article from this statement anyway. The fact that the bacteria happened to be in Chiron vaccine samples seems carrying no encyclopedic information about the bacteria or its impact. May be the remaining passage in the current article should be removed too?--Roman Riabenko (talk) 19:02, 9 February 2022 (UTC)

Why colour changes according to growth temperatures

Can any of you suggest a reason why the colonies of Serratia are different colours at different growth temperatures? If you could, please add the information to this page. Thx.— Preceding unsigned comment added by 137.154.16.31 (talk) 10:40, 11 October 2006 (UTC)

The red pigment produced by Serratia marcescens is prodigiosin. Its production, and that of another lipid (the surfactant serrawettin W1), is regulated by the product of a gene hexS. Mutants lacking HexS over-produce the first enzyme in prodigiosin production, encoded by the pigA gene (and the swrW gene, implicated in the synthesis of serrawettin W1. Presumably, this gene is temperature-sensitive.

Prodigiosin is a secondary metabolite of Serratia marcescens and its production is regulated by changes in growth medium as well as by teperature shifts.— Preceding unsigned comment added by Micjohn (talk • contribs) 18:11, 11 October 2006 (UTC)

References

1. TanikawaT, Nakagawa Y, Matsuyama T (2006). "Transcriptional downregulator hexS Controlling Prodigiosin and serrawettin W1 biosynthesis in Serratia marcescens". Microbiol Immunol. 50 (8): 587–96. PMID 16924143.{{cite journal}}: CS1 maint: multiple names: authors list (link)

Is toothbrushes bristles pinked a Serratia infection?

I'm a brazilian biologist and a have a question important to me: since last month my toothbrush bristles was pinked. Just my toothbrush, not the toothbrushes of my wife and sons. Then I used a new toothbrush, but at the day after first use, the bristles were pinked. I'm trying to understand this mistery for weeks, until now, when I found the text about Serratia marcescens. Is it possible my mouth/teeths/gum are infected? If yes, what I have to do, if Serratia is resistent to antibiotics? If not, what explains the toothbrushes pinked...? —Preceding unsigned comment added by 187.18.227.217 (talk) 09:18, 12 May 2011 (UTC)

Chlorhexidine (Corsodyl) is the first and best treatment for gingivitis. Serratia is not resistant to it. --192.38.89.32 (talk) 13:06, 21 May 2016 (UTC)

External links modified

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