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] defeated ] in the ], 2–6, 6–7<sup>(5–7)</sup>, 6–4, 6–4, 7–5 to win the men's singles tennis title at the 2022 ].<ref>{{Cite web|last=Carayol|first=Tumaini|date=30 January 2022|title=Rafael Nadal beats Medvedev in epic Australian Open final to claim 21st slam|url=https://www.theguardian.com/sport/2022/jan/30/australian-open-tennis-rafael-nadal-daniil-medvedev-match-report|access-date=30 January 2022|website=The Guardian}}</ref> It was his second ] title and 21st ] singles title overall, surpassing the all-time ] he had jointly held with ] and ].<ref>{{Cite web|title=Rafael Nadal wins 21st Grand Slam title at Australian Open, breaking tie with Novak Djokovic and Roger Federer|url=https://www.usopen.org/en_US/news/articles/2022-01-30/rafael_nadal_wins_21st_grand_slam_title_at_australian_open_breaking_tie_with_novak_djokovic_and_roger_federer.html|access-date=11 February 2022}}</ref> Nadal became the fourth man, after Djokovic, ] and ], to achieve the ], and the second in the ], joining Djokovic. He also became the first man in the Open Era to win an Australian Open final after losing the first two sets.<ref>{{Cite news|title= Nadal comes from two sets down to make history with 21st Slam|url=https://www.news.com.au/breaking-news/nadal-comes-from-two-sets-down-to-make-history-with-21st-slam/news-story/70a81434132985df91968bfd78b02677 |access-date=30 January 2022|newspaper=News.com.au — Australia's Leading News Site|date=30 January 2022 }}</ref><ref>{{cite web|url=https://www.bbc.com/sport/tennis/60183864|title=Rafael Nadal beats Daniil Medvedev from two sets down in Melbourne epic|date=20 January 2022|work=BBC Sport|accessdate=1 February 2022}}</ref>
] defeated ] in ], 2–6, 6–7<sup>(5–7)</sup>, 6–4, 6–4, 7–5 to win the men's singles tennis title at the 2022 Australian Open.<ref>{{Cite web|last=Carayol|first=Tumaini|date=30 January 2022|title=Rafael Nadal beats Medvedev in epic Australian Open final to claim 21st slam|url=https://www.theguardian.com/sport/2022/jan/30/australian-open-tennis-rafael-nadal-daniil-medvedev-match-report|access-date=30 January 2022|website=The Guardian}}</ref> It was his second ] title and 21st ] singles title overall, surpassing the all-time ] he had jointly held with ] and ].<ref>{{Cite web|title=Rafael Nadal wins 21st Grand Slam title at Australian Open, breaking tie with Novak Djokovic and Roger Federer|url=https://www.usopen.org/en_US/news/articles/2022-01-30/rafael_nadal_wins_21st_grand_slam_title_at_australian_open_breaking_tie_with_novak_djokovic_and_roger_federer.html|access-date=11 February 2022}}</ref> Nadal became the fourth man, after Djokovic, ] and ], to achieve the ], and the second in the ], joining Djokovic. He also became the first man in the Open Era to win an Australian Open final after losing the first two sets.<ref>{{Cite news|title= Nadal comes from two sets down to make history with 21st Slam|url=https://www.news.com.au/breaking-news/nadal-comes-from-two-sets-down-to-make-history-with-21st-slam/news-story/70a81434132985df91968bfd78b02677 |access-date=30 January 2022|newspaper=News.com.au — Australia's Leading News Site|date=30 January 2022 }}</ref><ref>{{cite web|url=https://www.bbc.com/sport/tennis/60183864|title=Rafael Nadal beats Daniil Medvedev from two sets down in Melbourne epic|date=20 January 2022|work=BBC Sport|accessdate=1 February 2022}}</ref>
Novak Djokovic was the three-time defending champion,<ref>{{Cite web|title=Dominant Djokovic Seals Historic Ninth Australian Open Crown {{!}} ATP Tour {{!}} Tennis|url=https://www.atptour.com/en/news/djokovic-medvedev-australian-open-2021-final|access-date=16 December 2021|website=ATP Tour}}</ref> but was unable to compete after his visa was cancelled shortly before the tournament began, due to an intervention from Australia's ] ], citing risks to public health and good order in Australia.<ref name="hawke">{{Cite web|date=14 January 2022|title=Immigration Minister cancels Novak Djokovic's visa|url=https://www.news.com.au/sport/tennis/live-updates-on-novak-djokovics-visa-cancellation-deportation-news/news-story/5cbaa65990a2bd6984072760bf2b9014|access-date=14 January 2022|website=news.com.au|language=en}}</ref><ref>{{cite web|url= https://minister.homeaffairs.gov.au/AlexHawke/Pages/statement-regarding-mr-novak-djokovic-2.aspx|title=Statement regarding Mr Novak Djokovic|publisher= Ministers for the Department of Home Affairs|access-date=21 January 2022 |url-status=live |archive-url= https://web.archive.org/web/20220118155932/https://minister.homeaffairs.gov.au/AlexHawke/Pages/statement-regarding-mr-novak-djokovic-2.aspx|archive-date=18 January 2022}}</ref> This meant Nadal was the only former champion (]) to compete in the tournament, with both Federer and ] sidelined by injury.
Novak Djokovic was the three-time defending champion,<ref>{{Cite web|title=Dominant Djokovic Seals Historic Ninth Australian Open Crown {{!}} ATP Tour {{!}} Tennis|url=https://www.atptour.com/en/news/djokovic-medvedev-australian-open-2021-final|access-date=16 December 2021|website=ATP Tour}}</ref> but was unable to compete after his visa was cancelled shortly before the tournament began, due to an intervention from Australia's ] ], citing risks to public health and good order in Australia.<ref name="hawke">{{Cite web|date=14 January 2022|title=Immigration Minister cancels Novak Djokovic's visa|url=https://www.news.com.au/sport/tennis/live-updates-on-novak-djokovics-visa-cancellation-deportation-news/news-story/5cbaa65990a2bd6984072760bf2b9014|access-date=14 January 2022|website=news.com.au|language=en}}</ref><ref>{{cite web|url= https://minister.homeaffairs.gov.au/AlexHawke/Pages/statement-regarding-mr-novak-djokovic-2.aspx|title=Statement regarding Mr Novak Djokovic|publisher= Ministers for the Department of Home Affairs|access-date=21 January 2022 |url-status=live |archive-url= https://web.archive.org/web/20220118155932/https://minister.homeaffairs.gov.au/AlexHawke/Pages/statement-regarding-mr-novak-djokovic-2.aspx|archive-date=18 January 2022}}</ref> This meant Nadal was the only former champion (]) to compete in the tournament, with both Federer and ] sidelined by injury.
Rafael Nadal defeated Daniil Medvedev in the final, 2–6, 6–7, 6–4, 6–4, 7–5 to win the men's singles tennis title at the 2022 Australian Open. It was his second Australian Open title and 21st major singles title overall, surpassing the all-time record he had jointly held with Novak Djokovic and Roger Federer. Nadal became the fourth man, after Djokovic, Roy Emerson and Rod Laver, to achieve the double career Grand Slam, and the second in the Open Era, joining Djokovic. He also became the first man in the Open Era to win an Australian Open final after losing the first two sets.
Novak Djokovic was the three-time defending champion, but was unable to compete after his visa was cancelled shortly before the tournament began, due to an intervention from Australia's Immigration MinisterAlex Hawke, citing risks to public health and good order in Australia. This meant Nadal was the only former champion (2009) to compete in the tournament, with both Federer and Stan Wawrinka sidelined by injury.
Djokovic retained the ATP No. 1 singles ranking despite being unable to defend his points after Medvedev and Alexander Zverev lost in the final and fourth round, respectively.
Matteo Berrettini became the first man born in the 1990s to reach the quarterfinals at all four majors in singles, and the first Italian man to reach the semifinals of the Australian Open.
The following are the seeded players. Seedings are based on ATP rankings as of 10 January 2022. Rank and points before are as of 17 January 2022.
As a result of pandemic-related adjustments to the ranking system and changes to the ATP Tour calendar in 2020 and 2021, ranking points after the tournament (as of 31 January 2022) were calculated as follows:
Players who were defending points from the 2020 tournament (i.e. players whose 2020 results exceeded or were equal to their 2021 results) had their 2020 points replaced by points from the 2022 tournament; as of 31 January 2022, these players could also count their 2021 points towards their ranking if the 2021 points exceeded their 19th best result (in other words, points from the 2021 and 2022 tournaments could be counted simultaneously instead of under the previous "better of" system)
Players who were defending points from the 2021 tournament (i.e. players whose 2021 points exceeded their 2020 points) had their 19th best result replaced by their points from the 2022 tournament; these players continued to count their 2021 points alongside their 2022 points at the end of the tournament because the 2021 tournament was delayed by three weeks compared to the normal schedule and the "better of" logic for calculating ATP ranking points had been discontinued
All players who have points from the 2021 tournament still counting towards their ranking on 31 January 2022 will have those points dropped on 21 February 2022 (52 weeks after the 2021 tournament) and replaced by their next best result
Note that this is a different ranking adjustment system than the one being used by the WTA for the women's event.
† The player's 2020 points were replaced by his 2022 points, and his 19th best result was replaced by his 2021 points. The 2021 points will be dropped three weeks after the end of the 2022 tournament.
§ The player was defending points from a 2020 ITF tournament.
Withdrawn players
The following players would have been seeded, but withdrew before the tournament began.
Djokovic lost his ability to compete when his visa to enter Australia was cancelled. Despite being granted a medical exemption to the tournament's COVID-19 vaccine requirement by Tennis Australia, the Australian Border Force confirmed that after being detained at Melbourne Airport for eight hours, Djokovic's visa had been cancelled and he would be denied entry to the country due to not meeting exemption criteria to Australia's vaccination requirements. Djokovic sought an injunction to prevent his deportation. The Federal Circuit and Family Court ruled in favour of Djokovic, ordered his release from detention and directed the federal government to pay his legal expenses.
On 14 January Minister for ImmigrationAlex Hawke used his discretionary power to cancel Djokovic's visa on health and good order grounds. Djokovic sought a judicial review against deportation, but three Federal Court of Australia judges unanimously rejected the review on 16 January, preventing him from defending his title.