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TAN-1057 C: Difference between revisions

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'''TAN-1057 C''' and '''TAN-1057 D''' are organic compounds found in the ''] sp.'' PK-74 bacterium. TAN-1057 C and D are closely related structurally as ]s. Also related are ] and TAN-1057 B, isolated from the same bacteria. The four compounds have been shown to be an effective ]s against ]-resistant strains of '']'' which act through the inhibition of ] biosynthesis.<ref name=Katayama>{{cite journal | author=Katayama, N ''et al.'' | title=TAN-1057 A-D, new antibiotics with potent antibacterial activity against methicillin-resistant Staphylococcus aureus. Taxonomy, fermentation and biological activity | journal=J. Antibiot. | year=1993 | pages=606–613 | volume=46 | issue=4 | pmid=8501003}}</ref> '''TAN-1057 C''' and '''TAN-1057 D''' are organic compounds found in the ''] sp.'' PK-74 bacterium. TAN-1057 C and D are closely related structurally as ]s. Also related are ] and TAN-1057 B, isolated from the same bacteria. The four compounds have been shown to be an effective ]s against ]-resistant strains of '']'' which act through the inhibition of ] biosynthesis.<ref name=Katayama>{{cite journal | author=Katayama, N ''et al.'' | title=TAN-1057 A-D, new antibiotics with potent antibacterial activity against methicillin-resistant Staphylococcus aureus. Taxonomy, fermentation and biological activity | journal=J. Antibiot. | year=1993 | pages=606–613 | volume=46 | issue=4 | pmid=8501003 | doi=10.7164/antibiotics.46.606}}</ref>


==References== ==References==

Revision as of 20:50, 24 May 2014

TAN-1057 C (top) and TAN-1057 D (bottom)
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
PubChem CID
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C13H25N9O3/c1-22-9(6-19-20-7-18-13(16)25)11(24)21-8(5-10(22)23)3-2-4-17-12(14)15/h7-9,19H,2-6H2,1H3,(H,21,24)(H4,14,15,17)(H3,16,18,20,25)/t8-,9+/m0/s1Key: PNFFUPQADHHLMN-DTWKUNHWSA-N
  • InChI=1/C13H25N9O3/c1-22-9(6-19-20-7-18-13(16)25)11(24)21-8(5-10(22)23)3-2-4-17-12(14)15/h7-9,19H,2-6H2,1H3,(H,21,24)(H4,14,15,17)(H3,16,18,20,25)/t8-,9+/m0/s1Key: PNFFUPQADHHLMN-DTWKUNHWBI
SMILES
  • O=C1N(C)(C(=O)N(C1)CCC/N=C(\N)N)CNN\C=N\C(=O)N
Properties
Chemical formula C13H25N9O3
Molar mass 355.403 g·mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). checkY verify (what is  ?) Infobox references
Chemical compound

TAN-1057 C and TAN-1057 D are organic compounds found in the Flexibacter sp. PK-74 bacterium. TAN-1057 C and D are closely related structurally as diastereomers. Also related are TAN-1057 A and TAN-1057 B, isolated from the same bacteria. The four compounds have been shown to be an effective antibiotics against methicillin-resistant strains of Staphylococcus aureus which act through the inhibition of protein biosynthesis.

References

  1. Katayama, N; et al. (1993). "TAN-1057 A-D, new antibiotics with potent antibacterial activity against methicillin-resistant Staphylococcus aureus. Taxonomy, fermentation and biological activity". J. Antibiot. 46 (4): 606–613. doi:10.7164/antibiotics.46.606. PMID 8501003. {{cite journal}}: Explicit use of et al. in: |author= (help)


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