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Hexylcaine: Difference between revisions

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Revision as of 11:59, 28 October 2014 edit86.27.40.30 (talk)No edit summary← Previous edit Revision as of 12:09, 28 October 2014 edit undoCheMoBot (talk | contribs)Bots141,565 edits Updating {{drugbox}} (no changed fields - added verified revid - updated 'CAS_number_Ref', 'verifiedrevid') per Chem/Drugbox validation (report errors or bugs)Next edit →
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{{Unreferenced stub|auto=yes|date=December 2009}} {{Unreferenced stub|auto=yes|date=December 2009}}
{{Drugbox {{Drugbox
| verifiedrevid = 415529194 | verifiedrevid = 461769300
| IUPAC_name = 1-cyclohexylaminopropan-2-yl benzoate | IUPAC_name = 1-cyclohexylaminopropan-2-yl benzoate
| image = Hexylcaine.PNG | image = Hexylcaine.PNG
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<!--Identifiers--> <!--Identifiers-->
| CASNo_Ref = {{cascite|correct|CAS}} | CASNo_Ref = {{cascite|correct|CAS}}
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 532-77-4 | CAS_number = 532-77-4
| ATC_prefix = none | ATC_prefix = none

Revision as of 12:09, 28 October 2014

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Find sources: "Hexylcaine" – news · newspapers · books · scholar · JSTOR (December 2009) (Learn how and when to remove this message)
Pharmaceutical compound
Hexylcaine
Clinical data
ATC code
  • none
Pharmacokinetic data
Elimination half-life<10 minutes
Identifiers
IUPAC name
  • 1-cyclohexylaminopropan-2-yl benzoate
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC16H23NO2
Molar mass261.359 g/mol g·mol
3D model (JSmol)
SMILES
  • O=C(OC(CNC1CCCCC1)C)c2ccccc2
InChI
  • InChI=1S/C16H23NO2/c1-13(12-17-15-10-6-3-7-11-15)19-16(18)14-8-4-2-5-9-14/h2,4-5,8-9,13,15,17H,3,6-7,10-12H2,1H3
  • Key:DKLKMKYDWHYZTD-UHFFFAOYSA-N
  (verify)

Hexylcaine hydrochloride, also called cyclaine (Merck) or osmocaine, is a short-acting local anesthetic. It acts by inhibiting sodium channel conduction. Overdose can lead to headache, tinnitus, numbness and tingling around the mouth and tongue, convulsions, inability to breathe, and decreased heart function.

Synthesis

Hexylcaine synthesis:
Local anesthetics (primarily sodium channel blockers) (N01B)
Esters by acid
Aminobenzoic
Benzoic
ArCO2- (not para-amino or Ph)
Amides
Combinations


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