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| '''Fast atom bombardment''' (FAB) is an ] technique used in ] in which an analyte and liquid matrix mixture is bombarded by a ~8KeV particle beam of usually inert gas such as ] or ]. Common matricies include ] and 3-nitrobenzyl alcohol (3-NBA). This technique is very closely related to (if not part of) ]. FAB is a relatively soft ionization technique and produces primarily |
'''Fast atom bombardment''' (FAB) is an ] technique used in ] in which an analyte and liquid matrix mixture is bombarded by a ~8KeV particle beam of usually inert gas such as ] or ]. Common matricies include ] and 3-nitrobenzyl alcohol (3-NBA). This technique is very closely related to (if not part of) ]. FAB is a relatively soft ionization technique and produces primarily protonated molecules denoted as <sup>+</sup> and deprotonated molecules such as <sup>+</sup>. The nature of its ionization products places it close to ] and ]. | ||
| ==External links== | ==External links== | ||
| * | * | ||
Revision as of 04:41, 26 December 2005
Fast atom bombardment (FAB) is an ionization technique used in mass spectrometry in which an analyte and liquid matrix mixture is bombarded by a ~8KeV particle beam of usually inert gas such as argon or xenon. Common matricies include glycerol and 3-nitrobenzyl alcohol (3-NBA). This technique is very closely related to (if not part of) secondary ion mass spectrometry. FAB is a relatively soft ionization technique and produces primarily protonated molecules denoted as and deprotonated molecules such as . The nature of its ionization products places it close to electrospray and MALDI.
External links
References
- Barber, M.; Bordoli, R.S.; Sedgewick, R.D.; Tyler, A.N., Nature, 293, 1981, pp270-275.
- Barber, M.; Bordoli, R.S.; Elliott, G.J.; Sedgewick, R.D.; Tyler, A.N., Analytical Chemistry, 54, 1982, pp645A-657A.