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| '''Orotidine 5'-monophosphate''' (OMP), also known as '''orotidylic acid,''' is a ] ] which is the last intermediate in the biosynthesis of ]. | '''Orotidine 5'-monophosphate''' (OMP), also known as '''orotidylic acid,''' is a ] ] which is the last intermediate in the biosynthesis of ]. OMP is formed from ] and ] by the enzyme ] | ||
| In humans, the enzyme ] converts OMP into ]. If UMP synthase is defective, ] can result. | In humans, the enzyme ] converts OMP into ]. If UMP synthase is defective, ] can result. | ||
Revision as of 11:28, 11 April 2011
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| Names | |
|---|---|
| IUPAC name 3--2,6-dioxo-pyrimidine-4-carboxylic acid | |
| Identifiers | |
| CAS Number | |
| 3D model (JSmol) | |
| MeSH | Orotidine+5'-monophosphate |
| PubChem CID | |
| CompTox Dashboard (EPA) | |
SMILES
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| Properties | |
| Chemical formula | C10H13N2O11P |
| Molar mass | 368.191 g/mol |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references | |
Orotidine 5'-monophosphate (OMP), also known as orotidylic acid, is a pyrimidine nucleotide which is the last intermediate in the biosynthesis of uridine monophosphate. OMP is formed from orotate and phosphoribosyl pyrophosphate by the enzyme Orotate phosphoribosyltransferase
In humans, the enzyme UMP synthase converts OMP into uridine 5'- monophosphate. If UMP synthase is defective, orotic aciduria can result.
| Nucleotide metabolic intermediates | |||||||||||
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| purine metabolism |
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| pyrimidine metabolism |
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