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Revision as of 20:55, 16 October 2011
Pharmaceutical compoundMonoclonal antibody | |
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Type | Whole antibody |
Source | Mouse |
Target | endotoxin |
Clinical data | |
Routes of administration | Intravenous infusion |
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ChemSpider | |
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Edobacomab, codenamed E5, is a mouse monoclonal antibody that was investigated as a possible treatment for sepsis caused by Gram-negative bacterial infections.
Further reading
- Greenman RL; Schein RM; Martin MA; et al. (1991). "A controlled clinical trial of E5 murine monoclonal IgM antibody to endotoxin in the treatment of gram-negative sepsis. The XOMA Sepsis Study Group". JAMA. 266 (8): 1097–102. doi:10.1001/jama.266.8.1097. PMID 1865542.
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ignored (help) - Bone RC; Balk RA; Fein AM; et al. (1995). "A second large controlled clinical study of E5, a monoclonal antibody to endotoxin: results of a prospective, multicenter, randomized, controlled trial. The E5 Sepsis Study Group". Crit. Care Med. 23 (6): 994–1006. PMID 7774238.
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ignored (help) - Angus DC; Birmingham MC; Balk RA; et al. (2000). "E5 murine monoclonal antiendotoxin antibody in gram-negative sepsis: a randomized controlled trial. E5 Study Investigators". JAMA. 283 (13): 1723–30. doi:10.1001/jama.283.13.1723. PMID 10755499.
{{cite journal}}
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ignored (help)
Monoclonal antibodies for infectious disease and toxins | |||||||||
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Bacterial |
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Toxin |
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This antiinfective drug article is a stub. You can help Misplaced Pages by expanding it. |
This monoclonal antibody–related article is a stub. You can help Misplaced Pages by expanding it. |