| Revision as of 13:40, 9 April 2012 editBeetstra (talk | contribs)Edit filter managers, Administrators172,084 edits Saving copy of the {{drugbox}} taken from revid 486424472 of page Fluconazole for the Chem/Drugbox validation project (updated: 'DrugBank').← Previous edit |
Revision as of 13:52, 9 April 2012 edit undoBeetstra (talk | contribs)Edit filter managers, Administrators172,084 edits Saving copy of the {{drugbox}} taken from revid 476476211 of page Galanin for the Chem/Drugbox validation project (updated: 'ChEMBL').Next edit → |
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{{ambox | text = This page contains a copy of the infobox ({{tl|drugbox}}) taken from revid of page ] with values updated to verified values.}} |
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{{ambox | text = This page contains a copy of the infobox ({{tl|drugbox}}) taken from revid of page ] with values updated to verified values.}} |
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{{Drugbox |
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{{Drugbox |
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| Verifiedfields = changed |
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| Verifiedfields = changed |
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| verifiedrevid = 456485284 |
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| verifiedrevid = 403760667 |
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| IUPAC_name = |
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| IUPAC_name = 2-(2,4-difluorophenyl)-<br />1,3-''bis''(1''H''-1,2,4-triazol-1-yl)propan-2-ol |
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| image = fluconazole_structure.svg |
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| image = |
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| width = 160 |
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| alt = |
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| image2 = Fluconazole-from-xtal-3D-balls.png |
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<!--Clinical data--> |
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<!--Clinical data--> |
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| tradename = Difulcan |
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| tradename = |
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| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> |
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| Drugs.com = {{drugs.com|monograph|fluconazole}} |
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| pregnancy_US = <!-- A / B / C / D / X --> |
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| MedlinePlus = a690002 |
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| pregnancy_category = D <small>(])</small>, C <small>(])</small> |
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| pregnancy_category = |
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| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled--> |
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| legal_status = S3/S4 <small>(Au)</small>, POM <small>(])</small>, ℞-only <small>(U.S.)</small> |
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| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII --> |
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| routes_of_administration = Oral, ], topical |
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| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM --> |
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| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> |
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| legal_status = |
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⚫ |
| routes_of_administration = |
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<!--Pharmacokinetic data--> |
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<!--Pharmacokinetic data--> |
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| bioavailability = >90% |
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| bioavailability = |
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| protein_bound = 11–12% |
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| protein_bound = |
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| metabolism = Hepatic 11% |
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| metabolism = |
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| elimination_half-life = 30 hours (range 20-50 hours) |
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| elimination_half-life = |
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| excretion = Renal 61–88% |
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| excretion = |
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<!--Identifiers--> |
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<!--Identifiers--> |
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| CASNo_Ref = {{cascite|correct|CAS}} |
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| CAS_number_Ref = {{cascite|correct|??}} |
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| CAS_number_Ref = {{cascite|correct|??}} |
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| CAS_number = 86386-73-4 |
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| CAS_number = |
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| ATC_prefix = D01 |
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| ATCvet = |
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| ATC_prefix = <!-- 'none' if uncategorised --> |
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| ATC_suffix = AC15 |
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| ATC_suffix = |
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| ATC_supplemental = {{ATC|J02|AC01}} |
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| PubChem = 3365 |
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| PubChem = |
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| DrugBank_Ref = {{drugbankcite|changed|drugbank}} |
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| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
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| DrugBank = DB00196 |
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| DrugBank = |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 3248 |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII = 8VZV102JFY |
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| KEGG_Ref = {{keggcite|correct|kegg}} |
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| KEGG = D00322 |
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| ChEBI_Ref = {{ebicite|correct|EBI}} |
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| ChEBI = 46081 |
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| ChEMBL_Ref = {{ebicite|correct|EBI}} |
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| ChEMBL_Ref = {{ebicite|correct|EBI}} |
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| ChEMBL = 106 |
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| ChEMBL = <!-- blanked - oldvalue: 501079 --> |
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| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} |
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| ChemSpiderID = NA |
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<!--Chemical data--> |
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<!--Chemical data--> |
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| chemical_formula = C146 H213 N43 O40 |
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| C=13 | H=12 | F=2 | N=6 | O=1 |
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| molecular_weight = 306.271 g/mol |
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| molecular_weight = 3210.5 |
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| smiles = Fc1ccc(c(F)c1)C(O)(Cn2ncnc2)Cn3ncnc3 |
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| InChI = 1/C13H12F2N6O/c14-10-1-2-11(12(15)3-10)13(22,4-20-8-16-6-18-20)5-21-9-17-7-19-21/h1-3,6-9,22H,4-5H2 |
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| InChIKey = RFHAOTPXVQNOHP-UHFFFAOYAZ |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI = 1S/C13H12F2N6O/c14-10-1-2-11(12(15)3-10)13(22,4-20-8-16-6-18-20)5-21-9-17-7-19-21/h1-3,6-9,22H,4-5H2 |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey = RFHAOTPXVQNOHP-UHFFFAOYSA-N |
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}} |
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}} |
