Nolatrexed - Misplaced Pages

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Nolatrexed
Names

IUPAC name 2-Amino-6-methyl-5-(4-pyridylthio)-1H-quinazolin-4-one
Identifiers
CAS Number	147149-76-6
3D model (JSmol)	Interactive image
PubChem CID	108189
CompTox Dashboard (EPA)	DTXSID3048281
SMILES CC1=C(C2=C(C=C1)NC(=NC2=O)N)SC3=CC=NC=C3
Properties
Chemical formula	C₁₄H₁₂N₄OS
Molar mass	284.34 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Y verify (what is ?) Infobox references

Chemical compound

Nolatrexed is a thymidylate synthase inhibitor.

References

Hughes AN, Rafi I, Griffin MJ; et al. (1999). "Phase I studies with the nonclassical antifolate nolatrexed dihydrochloride (AG337, THYMITAQ) administered orally for 5 days". Clin. Cancer Res. 5 (1): 111–8. PMID 9918208. {{cite journal}}: Explicit use of et al. in: |author= (help); Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)

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