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IUPAC name 1,3-Di(butanoyloxy)propan-2-yl butanoate | |
Other names Tributyrin | |
Identifiers | |
CAS Number | |
3D model (JSmol) | |
ChemSpider | |
ECHA InfoCard | 100.000.410 |
PubChem CID | |
UNII | |
CompTox Dashboard (EPA) | |
SMILES
| |
Properties | |
Chemical formula | C15H26O6 |
Molar mass | 302.367 g·mol |
Appearance | Oily liquid with bitter taste |
Density | 1.032 g/cm |
Melting point | −75 °C (−103 °F; 198 K) |
Solubility in water | Insoluble |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Y verify (what is ?) Infobox references |
Butyrin, also known as tributyrin, is a triglyceride naturally present in butter. It is an ester composed of butyric acid and glycerol. Among other things, it is used as an ingredient in making margarine. It is commonly occurring in butter and can be described as a liquid fat with an acrid taste.
Tributyrin is also used in microbiological laboratories to identify the bacterium Moraxella catarrhalis.
Tributyrin is a stable and rapidly absorbed prodrug of butyric acid which enhances antiproliferative effects of dihydroxycholecalciferol in human colon cancer cells.
References
- ^ Budavari, Susan, ed. (1996). The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals (12th ed.). Merck. ISBN 0911910123.
- Pérez, José L. (1990). "Butyrate esterase (4-methylumbelliferyl butyrate) spot test, a simple method for immediate identification of Moraxella (Branhamella) catarrhalis" (PDF Reprint). Journal of Clinical Microbiology. 28 (10). Washington, DC: American Society for Microbiology: 2347–2348. ISSN 1098-660X. PMC 268174. PMID 2121784.
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ignored (help) - Gaschott, Tanja (2001). "Tributyrin, a Stable and Rapidly Absorbed Prodrug of Butyric Acid, Enhances Antiproliferative Effects of Dihydroxycholecalciferol in Human Colon Cancer Cells". The Journal of Nutrition. 131 (6). Bethesda, MD: The American Society for Nutritional Sciences: 1839–1843. ISSN 1541-6100. PMID 11385076. Retrieved 2009-08-17.
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