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NIM811

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NIM811
Identifiers
CAS Number
3D model (JSmol)
PubChem CID
UNII
CompTox Dashboard (EPA)
SMILES
  • CC1C(=O)N(CC(=O)N((C(=O)N(C(=O)N((C(=O)N(C(=O)N(C(=O)N((C(=O)N((C(=O)N((C(=O)N((C(=O)N1)((C)C\C=C\C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)(C)CC)C)C
Properties
Chemical formula C62H111N11O12
Molar mass 1202.61
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). checkY verify (what is  ?) Infobox references
Chemical compound

NIM811 is a mitochondrial permeability transition inhibitor. Also known as N-methyl-4-isoleucine cyclosporin, it is a four-substituted cyclosporine that does not bind to cyclophilin A and therefore lacks immunosuppressive activity. Rather, NIM811 binds and inhibits cyclophilin.


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