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Axona

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This is an old revision of this page, as edited by Edgar181 (talk | contribs) at 14:37, 17 August 2011 (CAS#, etc.). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Revision as of 14:37, 17 August 2011 by Edgar181 (talk | contribs) (CAS#, etc.)(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff) Pharmaceutical compound
Axona
Clinical data
Other namesGlycerol trioctanoate; Tricaprylin
Routes of
administration
Oral
ATC code
  • None
Legal status
Legal status
Identifiers
IUPAC name
  • octanoate
CAS Number
PubChem CID
ChemSpider
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.007.898 Edit this at Wikidata
Chemical and physical data
FormulaC27H50O6
Molar mass470.68 g · mol g·mol
3D model (JSmol)
SMILES
  • O=C(OCC(OC(=O)CCCCCCC)COC(=O)CCCCCCC)CCCCCCC
InChI
  • InChI=1S/C27H50O6/c1-4-7-10-13-16-19-25(28)31-22-24(33-27(30)21-18-15-12-9-6-3)23-32-26(29)20-17-14-11-8-5-2/h24H,4-23H2,1-3H3
  • Key:VLPFTAMPNXLGLX-UHFFFAOYSA-N
  (verify)

Caprylidene (trade name Axona) is a medical food that was approved in March 2009 by the U.S. Food and Drug Administration for the "clinical dietary management of the metabolic processes associated with mild to moderate Alzheimer’s disease". Glucose metabolism by the brain is impaired in Alzheimer's disease, and it is proposed that ketone bodies may provide an alternative energy source. Caprylidene is a powdered form of caprylic triglyceride, a medium chain triglyceride (MCT) in which three molecules of caprylic acid are esterified with glycerol.

See also

References

  1. FDA-Approved Drugs 2009: Axona (caprylidene) CenterWatch. Cited 30 November 2009.
  2. Axona Drugs.com. Cited 30 November 2009.

Further reading

External links


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