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Pivhydrazine

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Revision as of 21:50, 18 September 2011 by BogBot (talk | contribs) (populated new fields in {{drugbox}} and reordered per bot approval. Report errors and suggestions to User_talk:BogBot)(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff) Pharmaceutical compound
Pivhydrazine
Clinical data
Other namesAngorvid, Betamezid, Neomarsilid, Pivazide, Pivhydrazine
Routes of
administration		Oral
ATC code
  • none
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
IUPAC name
  • N'-benzyl-2,2-dimethyl-propanehydrazide
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
ECHA InfoCard100.005.620 Edit this at Wikidata
Chemical and physical data
FormulaC12H18N2O
Molar mass206.28 g/mol g·mol
InChI
  • InChI=1S/C12H18N2O/c1-12(2,3)11(15)14-13-9-10-7-5-4-6-8-10/h4-8,13H,9H2,1-3H3,(H,14,15)
  • Key:FWWDFDMCZLOXQI-UHFFFAOYSA-N
  (verify)

Pivalylbenzhydrazine (trade name Tersavid), also known as pivazide or pivhydrazine, is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class that was previously used as an antidepressant in the 1960s, but has since been discontinued.

See also

References

  1. Herman, ZS; Sokola, A; Lenartowicz, H; Zieliński, M; Depta, L (1976). "The influence of antidepressive drugs on the level of acetylcholine and on the acetylcholinesterase activity in the brain of rats". Polish Journal of Pharmacology and Pharmacy. 28 (4): 313–321. ISSN 0301-0244. OCLC 1586290. PMID 981020. {{cite journal}}: Unknown parameter |month= ignored (help)
  2. Bolton, GC; Griffiths, LA (1979). "The metabolic disposition of [14C]pivhydrazine, [14C]mebanazine, and [14C]benzylhydrazine in the rat". Drug Metabolism and Disposition: the Biological Fate of Chemicals. 7 (6): 388–392. ISSN 0090-9556. OCLC 1784380. PMID 43225. Retrieved 2011-09-15. {{cite journal}}: Unknown parameter |month= ignored (help)
  3. Mikhaĭlova, TV; Gilev, AP; Khavronina-Gureeva, ZP (1969). Farmakologiia I Toksikologiia (in Russian). 32 (6): 652–656. ISSN 0014-8318. OCLC 1568906. PMID 5381593. {{cite journal}}: Missing or empty |title= (help); Unknown parameter |trans_title= ignored (|trans-title= suggested) (help)


Antidepressants (N06A)
Specific reuptake inhibitors and/or receptor modulators
SSRIsTooltip Selective serotonin reuptake inhibitors
SNRIsTooltip Serotonin–norepinephrine reuptake inhibitors
NRIsTooltip Norepinephrine reuptake inhibitors
NDRIsTooltip Norepinephrine–dopamine reuptake inhibitors
NaSSAsTooltip Noradrenergic and specific serotonergic antidepressants
SARIsTooltip Serotonin antagonist and reuptake inhibitors
SMSTooltip Serotonin modulator and stimulators
Others
Tricyclic and tetracyclic antidepressants
TCAsTooltip Tricyclic antidepressants
TeCAsTooltip Tetracyclic antidepressants
Others
Monoamine oxidase inhibitors
Non-selective
MAOATooltip Monoamine oxidase A-selective
MAOBTooltip Monoamine oxidase B-selective
Adjunctive therapies
Miscellaneous
Anxiolytics (N05B)
5-HT1ARTooltip 5-HT1A receptor agonists
GABAARTooltip GABAA receptor PAMsTooltip positive allosteric modulators
Hypnotics
Gabapentinoids
(α2δ VDCC blockers)
Antidepressants
Antipsychotics
Sympatholytics
(Antiadrenergics)
Others
Adrenergic receptor modulators
α1
Agonists
Antagonists
α2
Agonists
Antagonists
β
Agonists
Antagonists
Dopamine receptor modulators
D1-like
Agonists
PAMs
Antagonists
D2-like
Agonists
Antagonists
Serotonin receptor modulators
5-HT1
5-HT1A
5-HT1B
5-HT1D
5-HT1E
5-HT1F
5-HT2
5-HT2A
5-HT2B
5-HT2C
5-HT3–7
5-HT3
5-HT4
5-HT5A
5-HT6
5-HT7
Hydrazines


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