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Bivatuzumab mertansine: Difference between revisions

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{{Short description|Chemical compound}}
{{drugbox
{{one source|date=August 2014}}
| verifiedrevid = 400278734
{{Drugbox
| Verifiedfields = changed
| verifiedrevid = 447729255
| image = Mertansine mab structure.svg
<!-- Monoclonal antibody data -->
| type = mab | type = mab
| image = Mertansine mab structure.svg
| mab_type = mab | mab_type = mab
| source = zu/o | source = zu/o
| target = ] v6 | target = ] v6
<!-- Clinical data -->
| CAS_number =
| tradename =
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| legal_status =
| routes_of_administration =
<!-- Pharmacokinetic data -->
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
<!-- Identifiers -->
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number =
| ATC_prefix = none | ATC_prefix = none
| ATC_suffix = | ATC_suffix =
| PubChem = | PubChem =
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank = | DrugBank =
| chemical_formula =
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| molecular_weight =
| bioavailability = | ChemSpiderID = none
<!-- Chemical data -->
| protein_bound =
| chemical_formula =
| metabolism =
| molecular_weight =
| elimination_half-life =
| excretion =
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| legal_status =
| routes_of_administration =
}} }}
'''Bivatuzumab mertansine''' is a combination of ], a ]d ], and ], a ]. It is designed for the treatment of ].<ref>{{cite journal|doi=10.1158/1078-0432.CCR-06-0910|pmid=17062682|year=2006|last1=Tijink|first1=BM|last2=Buter|first2=J|last3=De Bree|first3=R|last4=Giaccone|first4=G|last5=Lang|first5=MS|last6=Staab|first6=A|last7=Leemans|first7=CR|last8=Van Dongen|first8=GA|title=A phase I dose escalation study with anti-CD44v6 bivatuzumab mertansine in patients with incurable squamous cell carcinoma of the head and neck or esophagus|volume=12|issue=20 Pt 1|pages=6064–72|journal=Clinical cancer research : an official journal of the American Association for Cancer Research}}</ref> '''Bivatuzumab mertansine''' is a combination of ], a ], and ], a ]. It is designed for the treatment of ].<ref>{{cite journal | vauthors = Tijink BM, Buter J, de Bree R, Giaccone G, Lang MS, Staab A, Leemans CR, van Dongen GA | display-authors = 6 | title = A phase I dose escalation study with anti-CD44v6 bivatuzumab mertansine in patients with incurable squamous cell carcinoma of the head and neck or esophagus | journal = Clinical Cancer Research | volume = 12 | issue = 20 Pt 1 | pages = 6064–72 | date = October 2006 | pmid = 17062682 | doi = 10.1158/1078-0432.CCR-06-0910 | doi-access = free }}</ref>


==References== == References ==
{{reflist}} {{reflist}}


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