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Ag+-exporting ATPase

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silver-exporting ATPase
Identifiers
EC no.7.2.2.15
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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In enzymology, an Ag+-exporting ATPase (EC 7.2.2.15) is an enzyme that catalyzes the chemical reaction

ATP + H2O + Agin {\displaystyle \rightleftharpoons } ADP + phosphate + Agout

The 3 substrates of this enzyme are ATP, H2O, and Ag+, whereas its 3 products are ADP, phosphate, and Ag+.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (Ag+-exporting).

References

  • Gupta A, Matsui K, Lo JF, Silver S (1999). "Molecular basis for resistance to silver cations in Salmonella". Nat. Med. 5 (2): 183–188. doi:10.1038/5545. PMID 9930866.
  • Bury NR, Grosell M, Grover AK, Wood CM (1999). "ATP-dependent silver transport across the basolateral membrane of rainbow trout gills". Toxicol. Appl. Pharmacol. 159 (1): 1–8. doi:10.1006/taap.1999.8706. PMID 10448119.
Hydrolases: acid anhydride hydrolases (EC 3.6)
3.6.1
3.6.2
3.6.3-4: ATPase
3.6.3
Cu++ (3.6.3.4)
Ca+ (3.6.3.8)
Na+/K+ (3.6.3.9)
H+/K+ (3.6.3.10)
Other P-type ATPase
3.6.4
3.6.5: GTPase
3.6.5.1: Heterotrimeric G protein
3.6.5.2: Small GTPase > Ras superfamily
3.6.5.3: Protein-synthesizing GTPase
3.6.5.5-6: Polymerization motors
Enzymes
Activity
Regulation
Classification
Kinetics
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