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α-Bisabolene synthase (EC 4.2.3.38, bisabolene synthase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((E)-α-bisabolene-forming).

This enzyme catalyses the following chemical reaction:

(2E,6E)-farnesyl diphosphate ${\displaystyle \rightleftharpoons }$ (E)-α-bisabolene + diphosphate

This synthase requires a divalent cation cofactor (Mg or, to a lesser extent, Mn) to neutralize the negative charge of the diphosphate leaving group.

References

1. Bohlmann J, Crock J, Jetter R, Croteau R (June 1998). "Terpenoid-based defenses in conifers: cDNA cloning, characterization, and functional expression of wound-inducible (E)-alpha-bisabolene synthase from grand fir (Abies grandis)". Proceedings of the National Academy of Sciences of the United States of America. 95 (12): 6756–61. Bibcode:1998PNAS...95.6756B. doi:10.1073/pnas.95.12.6756. PMC 22624. PMID 9618485.

External links

• Alpha-bisabolene+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

• Biology

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• EC 4.2.3
• EC 4.2 stubs