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Cheng Yung-chi

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Yung-chi Cheng
鄭永齊
Born (1944-12-29) December 29, 1944 (age 80)
England
Alma materTunghai University (BS)
Brown University (PhD)
Known forDiscovery of lamivudine
Discovery of emtricitabine
Cheng-Prusoff equation
Scientific career
FieldsBiochemical pharmacology
InstitutionsUniversity of Buffalo
Roswell Park Comprehensive Cancer Center
Academia Sinica
University of North Carolina at Chapel Hill
Yale University
Doctoral advisorR.E. Parks Jr.

Yung-chi Cheng (traditional Chinese: 鄭永齊; pinyin: Zhèng Yǒngqí; born December 29, 1944), also known as Tommy Cheng, is a Taiwanese-American pharmacologist. He is the Henry Bronson Professor of Pharmacology at Yale University, where he is the director of the Cheng laboratory at the Yale School of Medicine devoted to the study of antiviral drugs, and chairman of the Consortium for the Globalization of Chinese Medicine (CGCM).

Early life and education

Cheng was born in England on December 29, 1944, and later moved to Taiwan. After graduating from Tunghai University in 1966 with a Bachelor of Science (B.S.) in chemistry and biology, Cheng went to Canada and studied for a year at the University of Guelph.

Because his wife was a graduate student at Brown University, Cheng decided to transfer to Brown and pursue graduate studies in the United States. He spent his first two years at Brown University studying medicine before earning a Ph.D. in biochemical pharmacology in 1972 from the university, where he had been a research associate under professor R.E. Parks that same year.

Career

From September 1972 to June 1973, Cheng was a postdoctoral researcher under pharmacologist William Prusoff at the Yale School of Medicine. In the 1970s, together they co-formulated the Cheng-Prusoff equation to calculate the absolute inhibition constant Ki (IC50). In 1994, Cheng was elected a member of Academia Sinica.

Personal life

Cheng is married to Elaine H.C. Cheng, with whom he has two children.

References

  1. "New Haven's biotech boom". Yale Medicine Magazine. Yale School of Medicine. Fall 2000. Retrieved 2025-01-12.
  2. ^ Li, Huaqi (29 June 2020). "Applications of Traditional Chinese Medicine in Antiviral and Anticancer Drug Development: An Interview with Dr. Yung-Chi (Tommy) Cheng, PhD". Yale Journal of Biology and Medicine. 93 (2): 381–384. PMC 7309656. PMID 32607097.
  3. "Cover legend: Yung-Chi Cheng" (PDF). International Journal of Oncology. 29: 303. 2006.
  4. Capuano, Kristin. "Yung-Chi Cheng, PhD". Yale School of Medicine. Retrieved 2025-01-05.
  5. ^ "Who's Who in the ROC" (PDF). Executive Yuan. 20 October 2016. p. 365. Archived from the original (PDF) on 20 October 2016. Retrieved 5 May 2016.
  6. ^ Cheng Y, Prusoff WH (December 1973). "Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction". Biochem Pharmacol. 22 (23): 3099–108. doi:10.1016/0006-2952(73)90196-2. PMID 4202581.
  7. ^ "Curriculum Vitae: Cheng, Yung-chi". Yale School of Medicine. September 18, 2013. Retrieved 4 January 2025.

External links

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