Claybrook may refer to:
People
- Edwin Claybrook (1872–1931), American surgeon
- Elbert Pee Wee Claybrook (1912–1996), American jazz musician
- Joan Claybrook (born 1937), American lawyer and lobbyist
- John Claybrook (1872–1951), American businessman from Alabama
- William Claybrook (fl. 1600s), English priest
Places
- Claybrook House, house in London, England
- Claybrook House (Kearney, Missouri), historic house in the United States
Other
- Claybrook sign, medical phrase
See also
- Claybrooke Magna, a village and civil parish in Leicestershire, England
- Claybrooke Parva, a village and civil parish in Leicestershire, England
- Claybrooks, a surname
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