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Collapsed vein

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Medical injury

Collapsed veins are a common injury that results from repeated use of intravenous injections.

They can result from intravenous chemotherapy or when injection conditions are less than ideal, such as in the context of drug abuse.

Causes

Dehydration can cause temporary vein collapse.

Permanent vein collapse occurs as a consequence of:

  • Repeated injections, especially with blunt needles.
  • Poor injection technique.
  • Injection of substances which irritate the veins; in particular, fluids that are hypertonic (high osmolality), vasoactive, irritants, with an extreme pH (very acidic or alkaline),, many chemotherapeutic drugs or liquid methadone intended for oral use.

Smaller veins may collapse as a consequence of too much suction being used when pulling back against the syringe's plunger to check that the needle is in the vein. This will pull the sides of the vein together and, especially if inflamed, they may stick together causing the vein to block. Removing the needle too quickly after injecting can have a similar effect.

Mechanism

Veins may become temporarily blocked if the internal lining of the vein swells in response to repeated injury or irritation. This may be caused by the needle, the substance injected, or donating plasma.

Individual endothelial cells may change the structure of their cytoskeleton when a vein collapses to better deal with the increased shear stress.

Prognosis

Once endothelial swelling subsides, circulation will often become re-established. Collapsed veins may never recover. Many smaller veins are created by the body to circulate the blood, but they are not adequate for injections or IVs.

Research into solutions for patients with difficult venous access continues.

See also

References

  1. "Extravasation What is it? Patient leaflet". Milton Keynes University Hospital. Milton Keynes University Hospital NHS Foundation Trust. Retrieved 19 July 2023.
  2. "Guidelines for the Management of Extravasation of a Systemic Anti-Cancer Therapy including Cytotoxic Agents" (PDF). NHS England. West Midlands Expert Advisory Group for Systemic Anti-Cancer Therapy (SACT). Retrieved 19 July 2023.
  3. Walsh, Gabrielle (2008-01-01). "Difficult Peripheral Venous Access: Recognizing and Managing the Patient at Risk". Journal of the Association for Vascular Access. 13 (4): 198–203. doi:10.2309/java.13-4-7. ISSN 1552-8855.
  4. ^ Kreidieh, Firas Y (2016). "Overview, prevention and management of chemotherapy extravasation". World Journal of Clinical Oncology. 7 (1): 87. doi:10.5306/wjco.v7.i1.87. ISSN 2218-4333. PMC 4734939. PMID 26862492.
  5. "Extravasation injuries: prevention and management (neonatal guideline)". NHSGGC Paediatrics for Health Professionals NHSGGC Paediatrics for Health Professionals. NHS Greater Glasgow and Clyde (NHSGGC). Retrieved 19 July 2023.
  6. Haond, C.; Ribreau, C.; Boutherin-Falson, O.; Finet, M. (1999-10-01). "Laminar flow through a model of collapsed veins. Morphometric response of endothelial vascular cells to a longitudinal shear stress non uniform cross-wise". The European Physical Journal Applied Physics. 8 (1): 87–96. Bibcode:1999EPJAP...8...87H. doi:10.1051/epjap:1999233. ISSN 1286-0042.
  7. Little, Andrew; Jones, Drew G.; Alsbrooks, Kimberly (2022-05-04). "A narrative review of historic and current approaches for patients with difficult venous access: considerations for the emergency department". Expert Review of Medical Devices. 19 (5). doi:10.1080/17434440.2022.2095904. ISSN 1743-4440.
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