| deoxycytidine deaminase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.5.4.5 | ||||||||
| CAS no. | 37259-56-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a deoxycytidine deaminase (EC 3.5.4.5) is an enzyme that catalyzes the chemical reaction
- deoxycytidine + H2O deoxyuridine + NH3
deoxyuridine + NH3Thus, the two substrates of this enzyme are deoxycytidine and H2O, whereas its two products are deoxyuridine and NH3.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is cytidine/2'-deoxycytidine aminohydrolase. This enzyme participates in pyrimidine metabolism. As every deoxycytidine deaminase is also a cytidine deaminase, they share the same EC number. The recommended name assigned by the IUBMB is cytidine deaminase.
References
- Cohen SS (1953). "Studies on controlling mechanisms in the metabolism of virus-infected bacteria". Cold Spring Harbor Symposia on Quantitative Biology. 18: 221–35. doi:10.1101/sqb.1953.018.01.033. PMID 13168989.
| Hydrolases: carbon-nitrogen non-peptide (EC 3.5) | |
|---|---|
| 3.5.1: Linear amides / Amidohydrolases | |
| 3.5.2: Cyclic amides/ Amidohydrolases | |
| 3.5.3: Linear amidines/ Ureohydrolases | |
| 3.5.4: Cyclic amidines/ Aminohydrolases | |
| 3.5.5: Nitriles/ Aminohydrolases | |
| 3.5.99: Other | |
| Enzymes | |
|---|---|
| Activity | |
| Regulation | |
| Classification | |
| Kinetics | |
| Types |
|
This EC 3.5 enzyme-related article is a stub. You can help Misplaced Pages by expanding it. |