Dumaine and DuMaine are surnames. Notable people with either surname include:
- Bernard Dumaine (born 1953), French artist
- Cyrille Dumaine (1897–1946), Canadian politician
- Frederic C. Dumaine Jr. (1902–1997), American business executive
- Pierre DuMaine (1931–2019), American Roman Catholic bishop
Fictional characters:
- Dumaine, a character in Shakespeare's Love's Labour's Lost
Other uses
- Dumaine Street in the French Quarter of the city of New Orleans, USA.
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