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ETV7
Identifiers
Aliases	ETV7, TEL-2, TEL2, TELB, ETS variant 7, ETS variant transcription factor 7
External IDs	OMIM: 605255; HomoloGene: 56746; GeneCards: ETV7; OMA:ETV7 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) Band 6p21.31 Start 36,354,091 bp End 36,387,800 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in buccal mucosa cell triceps brachii muscle glutes gonad olfactory bulb skin of leg testicle beta cell skin of abdomen granulocyte n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA-binding transcription factor activity DNA binding sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding protein binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus nucleoplasm Biological process animal organ morphogenesis cell differentiation regulation of transcription, DNA-templated negative regulation of transcription by RNA polymerase II transcription by RNA polymerase II transcription, DNA-templated regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51513 n/a Ensembl ENSG00000010030 n/a UniProt Q9Y603 n/a RefSeq (mRNA) NM_001207035 NM_001207036 NM_001207037 NM_001207038 NM_001207039 NM_001207040 NM_001207041 NM_016135 n/a RefSeq (protein) NP_001193964 NP_001193965 NP_001193966 NP_001193967 NP_001193968 NP_001193969 NP_001193970 NP_057219 n/a Location (UCSC) Chr 6: 36.35 – 36.39 Mb n/a PubMed search n/a
Wikidata
View/Edit Human

Transcription factor ETV7 is a protein that in humans is encoded by the ETV7 gene.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000010030 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. Potter MD, Buijs A, Kreider B, van Rompaey L, Grosveld GC (Jun 2000). "Identification and characterization of a new human ETS-family transcription factor, TEL2, that is expressed in hematopoietic tissues and can associate with TEL1/ETV6". Blood. 95 (11): 3341–8. doi:10.1182/blood.V95.11.3341. PMID 10828014.
4. Gu X, Shin BH, Akbarali Y, Weiss A, Boltax J, Oettgen P, Libermann TA (Mar 2001). "Tel-2 is a novel transcriptional repressor related to the Ets factor Tel/ETV-6". J Biol Chem. 276 (12): 9421–36. doi:10.1074/jbc.M010070200. PMID 11108721.
5. "Entrez Gene: ETV7 ets variant gene 7 (TEL2 oncogene)".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Poirel H, Lopez RG, Lacronique V, et al. (2000). "Characterization of a novel ETS gene, TELB, encoding a protein structurally and functionally related to TEL". Oncogene. 19 (41): 4802–6. doi:10.1038/sj.onc.1203830. PMID 11032031. S2CID 38411496.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Boccuni P, MacGrogan D, Scandura JM, Nimer SD (2003). "The human L(3)MBT polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6)". J. Biol. Chem. 278 (17): 15412–20. doi:10.1074/jbc.M300592200. PMID 12588862.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Cardone M, Kandilci A, Carella C, et al. (2005). "The Novel ETS Factor TEL2 Cooperates with Myc in B Lymphomagenesis". Mol. Cell. Biol. 25 (6): 2395–405. doi:10.1128/MCB.25.6.2395-2405.2005. PMC 1061619. PMID 15743832.

External links

• Drosophila anterior open - The Interactive Fly

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