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A glidant is a substance that is added to a powder to improve its flowability. A glidant will only work at a certain range of concentrations. Above a certain concentration, the glidant will in fact function to inhibit flowability.
In tablet manufacture, glidants are usually added just prior to compression.
Examples
Examples of glidants include ascorbyl palmitate, calcium palmitate, magnesium stearate, fumed silica (colloidal silicon dioxide), starch and talc.
Mechanism of action
A glidant's effect is due to the counter-action of factors that cause poor flowability of powders. For instance, correcting surface irregularity, reducing interparticular friction and decreasing surface charge. The result is a decrease in the angle of repose which is an indication of an enhanced powder's flowability.
References
- KR 101440100, Kim, Dong Sup; Baik, Joo Hyun & Jung, Hyun Mook et al., "Use of ascorbyl palmitate and ascorbyl stearate as glidant for tablets", published 2014-09-17, assigned to Cosmax Bio Co. Ltd.
- "Vitamin & Supplement Recommendations for Your Health Concerns - Swanson®". www.swansonvitamins.com. Archived from the original on 2021-02-28. Retrieved 2021-02-05.
- "SMI: Talc as a Glidant & Lubricant". 2012 Specialty Minerals Inc. Archived from the original on 28 August 2008. Retrieved 19 March 2014.
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