A handshake is a one-on-one, interpersonal greeting ritual.
Handshake may also refer to:
- Handshake (computing), a computing term related to automated communication between two computing devices or programs
- Handshake deal, another term for an oral contract
- Handshaking lemma, a specific statement in graph theory
See also
- Hand Shakers, a Japanese anime television series
- Secret Handshake (disambiguation)
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