Heart of the West may refer to:
- Heart of the West, a 1907 collection of short stories by O. Henry
- Heart of the West, a 1936 screenplay by Doris Schroeder
- Heart of the West (film), a 1936 American Western film directed by Howard Bretherton and starring William Boyd
See also
- Hearts of the West (disambiguation)
- Heart of the Golden West, a 1942 American film
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