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 Artur Jorge (2001–02) Francisco Maturana (2002) Ilie Balaci (2002–03) Aad de Mos (2003–04) Ahmed Alajlani (2004) Marcos Paquetá (July 1, 2004–Dec 19, 2005, Mar 31, 2007–May 30, 2007)- Jose Kléber (Mar 24, 2006–May 28, 2006)
- José Peseiro (May 29, 2006–Jan 8, 2007)
- Toninho Cerezo (Jan 30, 2007–Mar 29, 2007)
- Cosmin Olăroiu (July 1, 2007–Feb 28, 2009)
- Catalin Necula (interim) (Feb 28, 2009–Mar 19, 2009)
 Georges Leekens (Apr 1, 2009–May 3, 2009)- Eric Gerets (Jul 1, 2009–Nov 13, 2010)
 Gabriel Calderon (Nov 14, 2010–June 30, 2011) Thomas Doll (July 22, 2011–Jan 20, 2012)- Heiko Bonan (interim) (Jan 21, 2012–Jan 30, 2012)
 Ivan Hašek (Jan 31, 2012–June 26, 2012) Antoine Kombouaré (June 27, 2012–Jan 30, 2013) Zlatko Dalić (Jan 31, 2013–May 27, 2013) Sami Al-Jaber (May 28, 2013–May 26, 2014)- Laurențiu Reghecampf (May 27, 2014–Feb 15, 2015)
- Marius Ciprian (interim) (Feb 16, 2015–Feb 28, 2015)
 Giorgos Donis (Mar 1, 2015–May 18, 2016)- Abdullatif Al-Hussaini (interim) (May 18, 2016–Jun 11, 2016)
 Gustavo Matosas (Jun 12, 2016–Sep 22, 2016)- Marius Ciprian (interim) (Sep 22, 2016–Oct 15, 2016)
- Ramón Díaz (Oct 15, 2016–Feb 21, 2018)
- Juan Brown (interim) (Feb 21, 2018–Jun 1, 2018)
- Jorge Jesus (Jun 5, 2018–Jan 31, 2019,
- Zoran Mamić (Jan 31, 2019–Apr 27, 2019)
- Péricles Chamusca (Apr 27, 2019–Jun 30, 2019)
- Razvan Lucescu (Jun 30, 2019–Feb 14, 2021)
- Rogério Micale (Feb 14, 2021–May 3 2021)
- Leonardo Jardim (June 2, 2021–Feb 14 2022)
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