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Methylenedioxynitazene

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Chemical compound Pharmaceutical compound
Methylenedioxynitazene
Identifiers
IUPAC name
  • 2-(2-((1,3-benzodioxol-5-yl)methyl)-5-nitro-1H-benzoimidazol-1-yl)-N,N-diethylethan-1-amine
CAS Number
Chemical and physical data
FormulaC21H24N4O4
Molar mass396.447 g·mol
3D model (JSmol)
SMILES
  • CCN(CC)CCn4c(Cc2ccc1OCOc1c2)nc3cc(()=O)ccc34
InChI
  • InChI=InChI=1S/C21H24N4O4/c1-3-23(4-2)9-10-24-18-7-6-16(25(26)27)13-17(18)22-21(24)12-15-5-8-19-20(11-15)29-14-28-19/h5-8,11,13H,3-4,9-10,12,14H2,1-2H3
  • Key:RRRJUZFZCVIDSM-UHFFFAOYSA-N

Methylenedioxynitazene (3',4'-Methylenedioxynitazene) is a benzimidazole derivative which has been sold as a designer drug over the internet and presumably has opioid effects. It is an analogue of etonitazene where the benzyl ring is substituted with a 3,4-methylenedioxy ring system rather than an ethoxy group. It was first reported in the UK in early 2024.

See also

References

  1. "Fourth addendum to ACMD report on the use and harms of 2-benzyl benzimidazole ('nitazene') and piperidine benzimidazolone ('brorphine-like') opioids" (PDF). Advisory Council on the Misuse of Drugs. 5 April 2024.


Opioid receptor modulators
μ-opioid
(MOR)
Agonists
(abridged;
full list)
Antagonists
δ-opioid
(DOR)
Agonists
Antagonists
κ-opioid
(KOR)
Agonists
Antagonists
Nociceptin
(NOP)
Agonists
Antagonists
Others
  • Others: Kyotorphin (met-enkephalin releaser/degradation stabilizer)


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