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Oswaldo Cruz

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Brazilian physician and bacteriologist (1872–1917) For other uses, see Oswaldo Cruz (disambiguation).
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In this Portuguese name, the first or maternal family name is Gonçalves and the second or paternal family name is Cruz.
Oswaldo Cruz
BornOswaldo Gonçalves Cruz
August 5, 1872
São Luís do Paraitinga, São Paulo, Empire of Brazil
DiedFebruary 11, 1917(1917-02-11) (aged 44)
Petrópolis, Rio de Janeiro, Brazil
NationalityBrazilian
CitizenshipBrazilian
Alma materFederal University of Rio de Janeiro
Scientific career
FieldsPhysician
InstitutionsInstituto Oswaldo Cruz

Oswaldo Gonçalves Cruz (Portuguese pronunciation: [ozˈvawdu ˈkɾus]; August 5, 1872 – February 11, 1917), was a Brazilian physician, pioneer bacteriologist, epidemiologist and public health officer and the founder of the Oswaldo Cruz Institute.

He occupied the fifth chair of the Brazilian Academy of Letters from 1912 until his death in 1917.

Early years

Oswaldo Gonçalves Cruz was born on August 5, 1872, in São Luis do Paraitinga, a small city in São Paulo Province, to the physician Bento Gonçalvez Cruz and Amália Bulhões Cruz. As a child, he moved to Rio de Janeiro with his family. At the age of 15 he started to study at the Faculty of Medicine of Rio de Janeiro and in 1892 he graduated as a medical doctor, with a thesis on water as vehicle for the propagation of microbes. Inspired by the work of Louis Pasteur, who had developed the germ theory of disease, four years later he went to Paris to specialize in bacteriology at the Pasteur Institute, which gathered the great names of this branch of science of that time. He was financed by his father-in-law, a wealthy Portuguese merchant.

Career

Work in Brazil

Cruz found that the seaport of Santos was ravaged by an epidemic of bubonic plague that threatened to reach Rio de Janeiro, and engaged himself immediately in the combat of this disease. The mayor of Rio de Janeiro authorized the construction of a plant for manufacturing the serum against the disease which had been developed at the Pasteur Institute by Alexandre Yersin and coworkers. He asked the institution for a scientist who could bring this know-how to Brazil. The Pasteur Institute responded that such a person was already available in Brazil: Oswaldo Cruz.

On May 25, 1900, the Federal Serum Therapy Institute was created, intended for the production of sera and vaccines against the bubonic plague, with Baron Pedro Afonso as director general and the young bacteriologist Oswaldo Cruz as technical director. The new institute was established in the old farm of Manguinhos at the western shores of Guanabara Bay. In 1902, Cruz accepted the office of director general of the institute and soon expanded the scope of its activities, now no longer restricted to the production of sera but also dedicated to basic and applied research and to the building of human resources. In the following year, Cruz was appointed director general of Public Health, a position corresponding to today's Brazilian Minister of Health.

Using the Federal Serum Therapy Institute as a technical-scientific base, he embarked on a quick succession of important sanitation campaigns. His first challenge was a series of yellow fever endemics, which had earned Rio de Janeiro the sinister reputation of 'Foreigners' Grave'. Between 1897 and 1906, 4,000 European immigrants had died there from the disease. Cruz pursued the new technique of eradicating mosquitoes and their breeding grounds, fumigating houses, and isolation of the ill. There was opposition to the campaign by many, including physicians, the military, and the poor, but the campaign was successful. Cruz was initially successful in the sanitary campaign against the bubonic plague, to which end he used obligatory notification of cases, isolation of sick people, treatment with the sera produced at Manguinhos and extermination of the rats populating the city.

Smallpox vaccination controversy

He was not successful in implementing a widespread vaccination against smallpox, due to popular resistance to it. In 1904, a smallpox epidemic was threatening the capital. In the first five months of the year, more than 1,800 people had been hospitalized. A law imposing smallpox vaccination of children had existed since 1837 but had never been put into practice. Therefore, on June 9, 1904, following a proposal by Oswaldo Cruz, the government presented a bill to the Congress requesting the reestablishment of obligatory smallpox vaccination. The extremely rigid and severe provisions of this instrument terrified the people. Popular opposition against Cruz increased sharply and opposition newspapers started a violent campaign against this and the federal government in general. Members of the parliament and labor unions protested. An anti-vaccination league was organized.

On November 10, the Vaccine Revolt exploded in Rio. Violent confrontations with the police ensued, with strikes, barricades, and shootings in the streets, as the population rose in protest against the government. On November 14, the cadets of the Military Academy joined the revolt, but were dispersed after intense shooting. The government declared a state of siege. On November 16, the uprising was controlled, but the obligatory vaccination was suspended.

In 1908, a violent smallpox epidemic made the people rush en masse to the vaccination units. Some 9,000 people died. Cruz was vindicated and his merit recognized.

Later work

Among the international scientific community, his prestige was already uncontested. In 1907, on occasion of the 14th International Congress on Hygiene and Demography in Berlin, Cruz was awarded with the gold medal in recognition of the sanitation of Rio de Janeiro. In 1909, he retired from the position as director general for Public Health, dedicating himself exclusively to the Manguinhos Institute, which has been named after him. From the institute he organized important scientific expeditions, which allowed a better knowledge about the health and life conditions in the interior of the country and contributed to the colonization of regions. Cruz eradicated urban yellow fever in the state of Pará. His sanitation campaign in the state of Amazonas allowed the completion of construction of the Madeira-Mamoré railroad, which had been interrupted due to the great number of deaths from malaria and yellow fever among the workers.

“The Oswaldo Cruz Institute”

In 1913, Cruz was elected a member of the Brazilian Academy of Arts and Letters. In 1915, due to health problems, he resigned from the directorship of the Oswaldo Cruz Institute and moved to Petrópolis, a small city in the mountains near Rio. On August 18, 1916, he was elected mayor of that city and outlined an extensive urbanization project he would not see implemented.

Death and legacy

Oswaldo Cruz on a 1986 50 Brazilian cruzados banknote

In the morning of February 11, 1917, at 44 years of age, he died of kidney failure in Petrópolis, Rio de Janeiro state.

As a consequence of the short, fruitful life of Oswaldo Cruz, an extremely important scientific and health institution was born, which marked the beginning of experimental medicine in Brazil in many areas. To this day it exerts a strong influence on Brazilian science, technology and public health.

In Brazil, several neighborhoods, schools, and public institutions are named after him. Some examples are the neighborhood of Oswaldo Cruz, Rio de Janeiro, the Rodovia Oswaldo Cruz in São Paulo, and the aforementioned health institute Oswaldo Cruz Foundation.

References

  1. ^ Stepan, "Cruz", p. 303.
  2. "Osvaldo Cruz". Academia Brasileira de Letras (in Brazilian Portuguese). Retrieved 2020-03-18.

Further reading

  • Cooper, Donald B. "Oswaldo Cruz and the Impact of Yellow Fever in Brazilian History," Bulletin of the Tulane Medical Faculty 26 (1967)L 49-52.
  • Fraga, Clementino. Vida e obra de Osvaldo Cruz. 1972. (tr. "Life and work of Oswaldo Cruz")
  • Stepan, Nancy. Beginnings of Brazilian Science: Oswaldo Cruz, Medical Research, and Policy, 1890-1920. New York: Science History Publications, 1981.
  • Stepan, Nancy Leys. "Osvaldo Gonçalves Cruz" in Encyclopedia of Latin American History and Culture, vol. 2, New York: Charles Scribner's Sons 1996.

External links

Preceded byRaimundo Correia (founder)
Brazilian Academy of Letters - Occupant of the 5th chair

1912 — 1917
Succeeded byAloísio de Castro
Patrons and members of the Brazilian Academy of Letters
Chairs
1 to 10

1 (Adelino Fontoura): Luís MuratAfonso d'Escragnolle TaunayIvan Monteiro de Barros LinsBernardo ÉlisEvandro Lins e SilvaAna Maria Machado
2 (Álvares de Azevedo): Coelho NetoJoão Neves da FontouraJoão Guimarães RosaMário PalmérioTarcísio PadilhaEduardo Giannetti da Fonseca
3 (Artur de Oliveira): Filinto de AlmeidaRoberto SimonsenAníbal Freire da FonsecaHerberto SalesCarlos Heitor ConyJoaquim Falcão
4 (Basílio da Gama): Aluísio AzevedoAlcides MaiaViana MoogCarlos Nejar
5 (Bernardo Guimarães): Raimundo CorreiaOswaldo CruzAloísio de CastroCândido Mota FilhoRachel de QueirozJosé Murilo de CarvalhoAilton Krenak
6 (Casimiro de Abreu): Teixeira de MeloArtur JaceguaiGoulart de AndradeBarbosa Lima SobrinhoRaimundo FaoroCícero Sandroni
7 (Castro Alves): Valentim MagalhãesEuclides da CunhaAfrânio PeixotoAfonso Pena JúniorHermes LimaPontes de MirandaDiná Silveira de QueirósSérgio Correia da CostaNelson Pereira dos SantosCacá Diegues
8 (Cláudio Manuel da Costa): Alberto de OliveiraOliveira VianaAustregésilo de AthaydeAntônio CaladoAntônio OlintoCleonice BerardinelliRicardo Cavaliere
9 (Gonçalves de Magalhães): Carlos Magalhães de AzeredoMarques RebeloCarlos Chagas FilhoAlberto da Costa e SilvaLilia Moritz Schwarcz
10 (Evaristo da Veiga): Rui BarbosaLaudelino FreireOsvaldo OricoOrígenes LessaLêdo IvoRosiska Darcy de Oliveira

Chairs
11 to 20

11 (Fagundes Varela): Lúcio de MendonçaPedro Augusto Carneiro LessaEduardo RamosJoão Luís AlvesAdelmar TavaresDeolindo CoutoDarcy RibeiroCelso FurtadoHélio JaguaribeIgnácio de Loyola Brandão
12 (França Júnior): Urbano Duarte de OliveiraAntônio Augusto de LimaVítor VianaJosé Carlos de Macedo SoaresAbgar RenaultLucas Moreira NevesAlfredo BosiPaulo Niemeyer Filho
13 (Francisco Otaviano): Alfredo d'Escragnolle TaunayFrancisco de CastroMartins JúniorSousa BandeiraHélio LoboAugusto MeyerFrancisco de Assis BarbosaSérgio Paulo RouanetRuy Castro
14 (Franklin Távora): Clóvis BeviláquaAntônio Carneiro LeãoFernando de AzevedoMiguel RealeCelso Lafer
15 (Gonçalves Dias): Olavo BilacAmadeu AmaralGuilherme de AlmeidaOdilo Costa FilhoMarcos BarbosaFernando Bastos de ÁvilaMarco Lucchesi
16 (Gregório de Matos): Araripe JúniorFélix PachecoPedro CalmonLygia Fagundes TellesJorge Caldeira
17 (Hipólito da Costa): Sílvio RomeroOsório Duque-EstradaEdgar Roquette-PintoÁlvaro LinsAntônio HouaissAffonso Arinos de Mello FrancoFernanda Montenegro
18 (João Francisco Lisboa): José VeríssimoBarão Homem de MeloAlberto FariaLuís CarlosPereira da SilvaPeregrino JúniorArnaldo Niskier
19 (Joaquim Caetano): Alcindo GuanabaraSilvério Gomes PimentaGustavo BarrosoSilva MeloAmérico Jacobina LacombeMarcos Almir MadeiraAntônio Carlos Secchin
20 (Joaquim Manuel de Macedo): Salvador de MendonçaEmílio de MenesesHumberto de CamposMúcio LeãoAurélio de Lira TavaresMurilo Melo FilhoGilberto Gil

Chairs
21 to 30

21 (Joaquim Serra): José do PatrocínioMário de AlencarOlegário MarianoÁlvaro MoreiraAdonias FilhoDias GomesRoberto CamposPaulo Coelho
22 (José Bonifácio the Younger): Medeiros e AlbuquerqueMiguel Osório de AlmeidaLuís Viana FilhoIvo PitanguyJoão Almino
23 (José de Alencar): Machado de AssisLafayette Rodrigues PereiraAlfredo PujolOtávio MangabeiraJorge AmadoZélia GattaiLuiz Paulo HortaAntônio Torres
24 (Júlio Ribeiro): Garcia RedondoLuís Guimarães FilhoManuel BandeiraCyro dos AnjosSábato MagaldiGeraldo Carneiro
25 (Junqueira Freire): Franklin DóriaArtur Orlando da SilvaAtaulfo de PaivaJosé Lins do RegoAfonso Arinos de Melo FrancoAlberto Venancio Filho
26 (Laurindo Rabelo): Guimarães PassosJoão do RioConstâncio AlvesRibeiro CoutoGilberto AmadoMauro MotaMarcos Vilaça
27 (Antônio Peregrino Maciel Monteiro): Joaquim NabucoDantas BarretoGregório da FonsecaLevi CarneiroOtávio de FariaEduardo PortellaAntonio CiceroEdgard Telles Ribeiro
28 (Manuel Antônio de Almeida): Inglês de SousaXavier MarquesMenotti Del PicchiaOscar Dias CorreiaDomício Proença Filho
29 (Martins Pena): Artur AzevedoVicente de CarvalhoCláudio de SousaJosué MontelloJosé MindlinGeraldo Holanda Cavalcanti
30 (Pardal Mallet): Pedro RabeloHeráclito GraçaAntônio AustregésiloAurélio Buarque de Holanda FerreiraNélida PiñonHeloísa Teixeira

Chairs
31 to 40

31 (Pedro Luís Pereira de Sousa): Luís Caetano Pereira Guimarães JúniorJoão Batista Ribeiro de Andrade FernandesPaulo SetúbalCassiano RicardoJosé Cândido de CarvalhoGeraldo França de LimaMoacyr ScliarMerval Pereira
32 (Manuel de Araújo Porto-Alegre): Carlos de LaetRamiz GalvãoViriato CorreiaJoracy CamargoGenolino AmadoAriano SuassunaZuenir Ventura
33 (Raul Pompeia): Domício da GamaFernando MagalhãesLuís EdmundoAfrânio CoutinhoEvanildo Bechara
34 (Sousa Caldas): João Manuel Pereira da SilvaJosé Maria da Silva Paranhos Jr.Lauro MüllerAquino CorreiaMagalhães JúniorCarlos Castelo BrancoJoão Ubaldo RibeiroZuenir VenturaEvaldo Cabral de Mello
35 (Tavares Bastos): Rodrigo OtávioRodrigo Otávio FilhoJosé Honório RodriguesCelso CunhaCândido Mendes de AlmeidaGodofredo de Oliveira Neto
36 (Teófilo Dias): Afonso CelsoClementino FragaPaulo CarneiroJosé Guilherme MerquiorJoão de ScantimburgoFernando Henrique Cardoso
37 (Tomás António Gonzaga): José Júlio da Silva RamosJosé de Alcântara MachadoGetúlio VargasAssis ChateaubriandJoão Cabral de Melo NetoIvan JunqueiraFerreira GullarArno Wehling
38 (Tobias Barreto): Graça AranhaAlberto Santos-DumontCelso VieiraMaurício Campos de MedeirosJosé Américo de AlmeidaJosé Sarney
39 (Francisco Adolfo de Varnhagen): Manuel de Oliveira LimaAlberto de FariaRocha PomboRodolfo GarciaElmano CardimOtto Lara ResendeRoberto MarinhoMarco MacielJosé Paulo Cavalcanti Filho
40 (José Maria da Silva Paranhos Sr.): Eduardo PradoAfonso ArinosMiguel CoutoAlceu Amoroso LimaEvaristo de Moraes FilhoEdmar Bacha

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