Samudrala is an Indian (Telugu) surname and may refer to:
- Samudrala Sr. (1902–1968), writer, producer, and director
- Samudrala Jr. (1923–1985), film writer and son of Samudrala Sr.
- Samudrala Venugopal Chary (fl. 1985–2009), Indian politician
- Ram Samudrala (born 1972), Indian-American professor of bioinformatics
See also
- Samandar (disambiguation)
- Samudra, Sanskrit word for the ocean
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