Say It Isn't So may refer to:
- Say It Isn't So (film), a 2001 comedy film starring Chris Klein and Heather Graham
- "Say It Isn't So" (Irving Berlin song), a 1932 song written by Irving Berlin.
- "Say It Isn't So" (Hall & Oates song), a 1983 single by Hall & Oates
- "Say It Isn't So", a song released in 1985 as a single by the Outfield from their album Play Deep
- "Say It Isn't So" (Bon Jovi song), a 2000 single by Bon Jovi
- "Say It Isn't So" (Gareth Gates song), a 2003 single by Gareth Gates
See also
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