Nitrazepate: Difference between revisions

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Revision as of 16:56, 10 September 2011 editCheMoBot (talk \| contribs)Bots141,565 edits Updating {{drugbox}} (no changed fields - added verified revid - updated 'DrugBank_Ref', 'UNII_Ref', 'ChEMBL_Ref', 'ChEBI_Ref', 'KEGG_Ref', 'ChEBI_Ref') per Chem/Drugbox validation (report [[Misplaced Pages talk:WikiProject_Pharmacology\|er← Previous edit		Revision as of 22:17, 18 September 2011 edit undoBogBot (talk \| contribs)Bots53,132 edits populated new fields in {{drugbox}} and reordered per bot approval. Report errors and suggestions to User_talk:BogBot Next edit →
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	{{Drugbox\| verifiedrevid = 431364926		{{Drugbox
			\| verifiedrevid = 431364926
		⚫	\| IUPAC_name = (''RS'')-7-nitro-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepine-3-carboxylate
	\|
	\| ~~drug_name~~ = Nitrazepate		\| image = Nitrazepate.png
⚫	\|IUPAC_name = (''RS'')-7-nitro-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepine-3-carboxylate
⚫	\| ~~image~~=Nitrazepate~~.png~~
⚫	\| imagename = 1 : 1 mixture (racemate)
	\| width = 250px		\| width = 250px
		⚫	\| imagename = 1 : 1 mixture (racemate)
⚫	\| CAS_number=5571-84-6
		⚫	\| drug_name = Nitrazepate
	\| ATC_prefix=

	\| ATC_suffix=
			<!--Clinical data-->
	\| ATC_supplemental=
			\| tradename =
⚫	\| PubChem=21740
		⚫	\| legal_status =

			<!--Pharmacokinetic data-->
		⚫	\| bioavailability =
		⚫	\| metabolism =
		⚫	\| elimination_half-life =
		⚫	\| excretion =

			<!--Identifiers-->
		⚫	\| CAS_number = 5571-84-6
		⚫	\| PubChem = 21740
	\| DrugBank_Ref = {{drugbankcite\|correct\|drugbank}}		\| DrugBank_Ref = {{drugbankcite\|correct\|drugbank}}
		⚫	\| ChemSpiderID_Ref = {{chemspidercite\|correct\|chemspider}}
	\| DrugBank=
		⚫	\| ChemSpiderID = 20436
⚫	\| C=16 \| H=11 \| N=3 \| O=5

			<!--Chemical data-->
		⚫	\| C=16 \| H=11 \| N=3 \| O=5
	\| molecular_weight = 325.275		\| molecular_weight = 325.275
	\| smiles = c3ccccc3C(=NC1C(O)=O)c2cc((=O)=O)ccc2NC1=O		\| smiles = c3ccccc3C(=NC1C(O)=O)c2cc((=O)=O)ccc2NC1=O
	\| ~~ChemSpiderID_Ref~~ = {{~~chemspidercite~~\|correct\|chemspider}}		\| StdInChI_Ref = {{stdinchicite\|correct\|chemspider}}
		⚫	\| StdInChI = 1S/C16H11N3O5/c20-15-14(16(21)22)18-13(9-4-2-1-3-5-9)11-8-10(19(23)24)6-7-12(11)17-15/h1-8,14H,(H,17,20)(H,21,22)
⚫	\| ChemSpiderID = 20436
		⚫	\| StdInChIKey_Ref = {{stdinchicite\|correct\|chemspider}}
	\| SMILES = (=O)c3cc\1c(NC(=O)C(/N=C/1c2ccccc2)C(=O)O)cc3
⚫	\| ~~StdInChI_Ref~~ = {{~~stdinchicite~~\|correct\|chemspider}}
⚫	\| StdInChI=1S/C16H11N3O5/c20-15-14(16(21)22)18-13(9-4-2-1-3-5-9)11-8-10(19(23)24)6-7-12(11)17-15/h1-8,14H,(H,17,20)(H,21,22)
⚫	\| StdInChIKey_Ref = {{stdinchicite\|correct\|chemspider}}
	\| StdInChIKey = JPEUYYKTUFRADV-UHFFFAOYSA-N		\| StdInChIKey = JPEUYYKTUFRADV-UHFFFAOYSA-N
⚫	\| bioavailability=
⚫	\| metabolism =
⚫	\| elimination_half-life=
⚫	\| excretion =
	\| pregnancy_category =
⚫	\| legal_status =
	\| routes_of_administration=
	}}		}}

Revision as of 22:17, 18 September 2011

Pharmaceutical compound

Nitrazepate
Identifiers

IUPAC name (RS)-7-nitro-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepine-3-carboxylate
CAS Number	5571-84-6
PubChem CID	21740
ChemSpider	20436
CompTox Dashboard (EPA)	DTXSID80971082
Chemical and physical data
Formula	C₁₆H₁₁N₃O₅
Molar mass	325.275 g·mol
3D model (JSmol)	Interactive image
SMILES c3ccccc3C(=NC1C(O)=O)c2cc((=O)=O)ccc2NC1=O
InChI InChI=1S/C16H11N3O5/c20-15-14(16(21)22)18-13(9-4-2-1-3-5-9)11-8-10(19(23)24)6-7-12(11)17-15/h1-8,14H,(H,17,20)(H,21,22) Key:JPEUYYKTUFRADV-UHFFFAOYSA-N
(verify)

Nitrazepate (Lorzem) is a drug which is a benzodiazepine derivative and has anxiolytic properties. It is normally produced as its potassium salt, potassium nitrazepate.

References

"nitrazepate". psychotropics.dk. 2003. Retrieved 7 December 2009.

v t e Benzodiazepines
1,4-Benzodiazepines	2-Oxoquazepam 3-Hydroxyphenazepam Bromazepam BMS-906024* Camazepam Carburazepam Chlordiazepoxide Cinazepam Cinolazepam Clonazepam Cloniprazepam Clorazepate Cyprazepam Delorazepam Demoxepam Desmethylflunitrazepam Devazepide* Diazepam Diclazepam Difludiazepam Doxefazepam Elfazepam Ethyl carfluzepate Ethyl dirazepate Ethyl loflazepate Flubromazepam Fletazepam Fludiazepam Flunitrazepam Flurazepam Flutemazepam Flutoprazepam Fosazepam Gidazepam Halazepam Iclazepam Irazepine* Kenazepine Ketazolam Lorazepam Lormetazepam Lufuradom* Meclonazepam Medazepam Menitrazepam Metaclazepam Motrazepam N-Desalkylflurazepam Nifoxipam Nimetazepam Nitemazepam Nitrazepam Nitrazepate Nordazepam Nortetrazepam Oxazepam Phenazepam Pinazepam Pivoxazepam Prazepam Proflazepam Quazepam QH-II-66 Reclazepam RO4491533* Ro05-4082 Ro5-4864* Ro07-5220 Ro07-9749 Ro20-8065 Ro20-8552 SH-I-048A Sulazepam Temazepam Tetrazepam Tifluadom* Timelotem* Tolufazepam Triflunordazepam Tuclazepam Uldazepam
1,5-Benzodiazepines	Arfendazam Clobazam CP-1414S Lofendazam Triflubazam
2,3-Benzodiazepines*	Girisopam GYKI-52466 GYKI-52895 Nerisopam Talampanel Tofisopam
Triazolobenzodiazepines	Adinazolam Alprazolam Balovaptan* Bromazolam Clonazolam Estazolam Fluadinazolam Flualprazolam Flubromazolam Flunitrazolam Nitrazolam Phenazolam Pyrazolam Rilmazolam (active metabolite of Rilmazafone) Triazolam
Imidazobenzodiazepines	Bretazenil Climazolam EVT-201 FG-8205 Flumazenil GL-II-73 Imidazenil I-Iomazenil L-655,708 Loprazolam Midazolam PWZ-029 Remimazolam Ro15-4513 Ro48-6791 Ro48-8684 Ro4938581 Sarmazenil SH-053-R-CH3-2′F
Oxazolobenzodiazepines	Cloxazolam Flutazolam Haloxazolam Mexazolam Oxazolam
Thienodiazepines	Bentazepam Clotiazepam Ro09-9212
Thienotriazolodiazepines	α-Hydroxyetizolam Apafant* Brotizolam Ciclotizolam Clotizolam Deschloroclotizolam Deschloroetizolam Etizolam Flubrotizolam Fluclotizolam Fluetizolam Israpafant* JQ1* Metizolam
Thienobenzodiazepines*	Olanzapine Telenzepine
Pyridodiazepines	Lopirazepam
Pyridotriazolodiazepines	Zapizolam
Pyrazolodiazepines	Razobazam* Ripazepam Zolazepam Zomebazam Zometapine*
Pyrrolodiazepines	Premazepam
Tetrahydroisoquinobenzodiazepines	Clazolam
Pyrrolobenzodiazepines*	Anthramycin
Benzodiazepine prodrugs	Alprazolam triazolobenzophenone Avizafone Rilmazafone
* atypical activity profile (not GABA_A receptor ligands)

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Revision as of 22:17, 18 September 2011

See also

References