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Revision as of 14:36, 29 May 2012 by Dcirovic (talk | contribs) (→References)(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff) Pharmaceutical compoundIdentifiers | |
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IUPAC name
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CompTox Dashboard (EPA) | |
Chemical and physical data | |
Formula | C19H19N3O3 |
Molar mass | 337.372 g/mol g·mol |
3D model (JSmol) | |
SMILES
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MMPIP is a drug used in scientific research that acts as a selective antagonist for the metabotropic glutamate receptor subtype mGluR7. This receptor subtype appears to be involved in the downstream response to cocaine in the brain.
References
- Suzuki G, Tsukamoto N, Fushiki H, Kawagishi A, Nakamura M, Kurihara H, Mitsuya M, Ohkubo M, Ohta H (2007). "In vitro pharmacological characterization of novel isoxazolopyridone derivatives as allosteric metabotropic glutamate receptor 7 antagonists". The Journal of Pharmacology and Experimental Therapeutics. 323 (1): 147–56. doi:10.1124/jpet.107.124701. PMID 17609420.
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ignored (help)CS1 maint: multiple names: authors list (link) - Li X, Li J, Peng XQ, Spiller K, Gardner EL, Xi ZX (2009). "Metabotropic glutamate receptor 7 modulates the rewarding effects of cocaine in rats: involvement of a ventral pallidal GABAergic mechanism". Neuropsychopharmacology. 34 (7): 1783–96. doi:10.1038/npp.2008.236. PMID 19158667.
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ignored (help)CS1 maint: multiple names: authors list (link)
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