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Tetrahydrofuranitazene

Identifiers
IUPAC name 2-(2-((2,3-dihydrobenzofuran-5-yl)methyl)-5-nitro-1H-benzoimidazol-1-yl)-N,N-diethylethan-1-amine
PubChem CID	168310596
Chemical and physical data
Formula	C22H26N4O3
Molar mass	394.475 g·mol
3D model (JSmol)	Interactive image
SMILES CCN(CC)CCN1C(CC2=CC=C(OCC3)C3=C2)=NC4=CC(()=O)=CC=C14
InChI InChI=1S/C22H26N4O3/c1-3-24(4-2)10-11-25-20-7-6-18(26(27)28)15-19(20)23-22(25)14-16-5-8-21-17(13-16)9-12-29-21/h5-8,13,15H,3-4,9-12,14H2,1-2H3 Key:IPSJQZUMCSELFZ-UHFFFAOYSA-N

Ethyleneoxynitazene (Tetrahydrofuranitazene) is a benzimidazole derivative which has been sold as a designer drug over the internet and presumably has opioid effects. It is an analogue of etonitazene where the 4-ethoxy group attached to the benzyl ring has been cyclised round to the 3-position to form a 2,3-dihydrobenzofuran ring system. It was first reported in Estonia in February 2023, subsequently in the UK in late 2023 and in China July 1st.

See also

• Etonitazepyne
• Etomethazene
• Isotonitazene
• Methylenedioxynitazene
• List of benzimidazole opioids
• Substituted benzofuran

References

1. "New psychoactive substances - the current situation in Europe" (PDF). European Drug Report. European Union Drugs Agency (EUDA). 2024.
2. "Third addendum to ACMD report on the use and harms of 2-benzyl benzimidazole ('nitazene') and piperidine benzimidazolone ('brorphine-like') opioids" (PDF). Advisory Council on the Misuse of Drugs. 15 December 2023.
3. "Reddit - Dive into anything". www.reddit.com. Retrieved 2024-10-16.

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