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HLA-B54

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Human leukocyte antigen serotype
major histocompatibility complex (human), class I, B54
Alleles B*5401
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*5401
Locus chr.6 6p21.31

HLA-B54 (B54) is an HLA-B serotype. B54 is a split antigen from the B22 broad antigen, sister serotypes are B55 and B56. The serotype identifies the more common HLA-B*55 gene products.

Serotype

B54 and B22 serotype recognition of HLA B*5401 allele
B*54 B54 B22 Sample
allele % % size (N)
5401 67 3 631

Allele distribution

HLA B*5401 frequencies
freq
ref. Population (%)
USA Hawaii Okinawa 10.6
Japan Central 7.7
South Korea (3) 5.9
China Guangzhou 4.5
Thailand (3) 4.1
China Inner Mongolia 3.4
China North Han 3.3
China Beijing Shijiazhuang Tianjian Han 3.0
China South Han 2.5
Russia Tuva pop 2 2.2
China Guangxi Maonan 1.9
Thailand 1.8
Taiwan Thao 1.7
China Tibet Autonomous Region Tibetans 1.3

See also

References

  1. Hildebrand, W. H.; Madrigal, J. A.; Little, A. M.; Parham, P. (1992). "HLA-Bw22: a family of molecules with identity to HLA-B7 in the alpha 1-helix". Journal of Immunology. 148 (4): 1155–1162. PMID 1737933.
  2. Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.
  3. derived from IMGT/HLA
  4. ^ Middleton, D.; Menchaca, L.; Rood, H.; Komerofsky, R. (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–407. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.
HLA-B serotypes and allele groups
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