Misplaced Pages

HLA-B73

Article snapshot taken from[REDACTED] with creative commons attribution-sharealike license. Give it a read and then ask your questions in the chat. We can research this topic together.
(Redirected from HLA-B*73) Human leukocyte antigen serotype
major histocompatibility complex (human), class I, B73
Alleles B*7301
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*7301
Locus chr.6 6p21.31

HLA-B73 (B73) is an HLA-B serotype. The serotype identifies the HLA-B*7301 gene product. Part of B*7301 is similar to the HLA-B22 family, however part resembles the domains seen in other apes. B73 is more common in Western Indian Ocean, Mediterranean and Africa. (For terminology help see: HLA-serotype tutorial)

Serotype

B*73:01 is one of the four B alleles that reacts with neither Bw4 nor Bw6. The others are B*18:06, B*46:01, and B*55:03.

B73 serotype recognition of B*7301 allele-group gene products
B*73 B73 Other Sample
allele % % size (N)
7301 22 69 106

B*7301 frequencies

HLA B*7301 frequencies
freq
ref. Population (%)
Parsi (Karachi, Pakistan) 4.9
United Arab Emirates 2.0
Italy 2.0
Seri (Sonora, Mexico) 1.5
Purépecha (Michoacán, Mexico) 1.5
Jews (Israel) (*2 studies) 1.2
Beti (Cameroon) 1.1
Casablanca (Morocco) 0.9
Tbilisi (Georgia) 0.9
Mossi (Burkina Faso) 0.9
Bulgaria 0.9
Sudanese 0.8
Tuva (Russia) (2) 0.8
Oman 0.8
Bamileke (Cameroon) 0.6
Pathan (Pakistan) 0.5
Khalkha (Mongolia) 0.5
Druse Arabs (Israel) 0.5
Baloch (Iran) 0.5
Manchester (England) 0.5
Algeria (1) 0.5
Turkey 0.4
Amman (Jordan) 0.3
Shona (Harare, Zimbabwe) 0.2
Republic of Macedonia 0.2
Nandi (Kenya) 0.2
Luo (Kenya) 0.2
Campania (Italy) 0.2
Greece 0.2

References

  1. Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.
  2. Hoffmann HJ, Kristensen TJ, Jensen TG, Graugaard B, Lamm LU (1995). "Antigenic characteristics and cDNA sequences of HLA-B73". Eur. J. Immunogenet. 22 (3): 231–40. doi:10.1111/j.1744-313X.1995.tb00237.x. PMID 8547229.
  3. Voorter, CE; van der Vlies, S; Kik, M; van den Berg-Loonen, EM (October 2000). "Unexpected Bw4 and Bw6 reactivity patterns in new alleles". Tissue Antigens. 56 (4): 363–70. doi:10.1034/j.1399-0039.2000.560409.x. PMID 11098937.
  4. derived from IMGT/HLA
  5. ^ Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database". Tissue Antigens. 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.
HLA-B serotypes and allele groups
Category:
HLA-B73 Add topic