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NBoc-DMT

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Pharmaceutical compound
NBoc-DMT
Clinical data
Other namesNB-DMT; DMT-BOC; N′-t-BOC-DMT; N′-tert-Butoxycarbonyl-N,N-dimethyltryptamine
Drug classSerotonergic psychedelic; Hallucinogen; Serotonin receptor agonist; Serotonin 5-HT2A receptor agonist
Legal status
Legal status
  • Illegal in Russia
Identifiers
IUPAC name
  • tert-butyl 3-indole-1-carboxylate
PubChem CID
Chemical and physical data
FormulaC17H24N2O2
Molar mass288.391 g·mol
3D model (JSmol)
SMILES
  • CC(C)(C)OC(=O)N1C=C(C2=CC=CC=C21)CCN(C)C
InChI
  • InChI=1S/C17H24N2O2/c1-17(2,3)21-16(20)19-12-13(10-11-18(4)5)14-8-6-7-9-15(14)19/h6-9,12H,10-11H2,1-5H3
  • Key:IKVMWFRRDDILJA-UHFFFAOYSA-N

NBoc-DMT, or NB-DMT, also known as N1-tert-butoxycarbonyl-N,N-dimethyltryptamine, is a serotonergic psychedelic of the tryptamine family. It is a novel designer and recreational drug and is a synthetic modification of dimethyltryptamine (DMT) with an N′-tert-butyloxycarbonyl (NBoc) group. NB-DMT is said to be a "prodrug" of DMT that decomposes into DMT when the compound is heated (e.g., with smoking or vaping), and may also be useful as an orally active prodrug of DMT, unlike DMT itself which is inactive when taken orally. It has been claimed to have about 25% of the potency of DMT by weight. The drug was first detected as a designer drug being sold online by February 2024. NB-DMT is a Schedule I controlled substance in Russia. A number of other NBoc designer drugs have also been encountered.

See also

References

  1. ^ "DMT BOC (NB-DMT)". АИПСИН (in Russian). Retrieved 23 January 2025.
  2. ^ "Tert-butyl 3-[2-(dimethylamino)ethyl]indole-1-carboxylate". PubChem. Retrieved 23 January 2025.
  3. Alexander M, Duncton J, Clark S. N,n-dimethyltryptamine and related psychedelics and uses thereof. US 2024/0116870
  4. Buchner M. Novel n,n-dimethyltryptamine (dmt) derivatives and uses thereof. WO 2024/121253
  5. Johnson CS, Bogun B (2019). "Chemical camouflage: illicit drug concealment using di-tert-butyldicarbonate". Australian Journal of Forensic Sciences. 51: S217 – S219. doi:10.1080/00450618.2019.1569135. S2CID 86747489.


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